Frommhold H
Universitätsklinik für Strahlentherapie, Innsbruck.
Rontgenblatter. 1989 May;42(5):216-8.
Radio-oncology ranks highly in the treatment concept of tumours of the head and neck. Radiotherapy alone yields excellent rates of remission and cure with good cosmetic and functional results if applied in an early stage. Advanced tumours require the use of combined treatment modalities including surgery, radiotherapy and chemotherapy. The results of radiotherapy show a close relation to the applied dose in the target volume. This dose depends on the histology of the tumour, its localisation, its size, and the extent of involvement of lymph nodes. Radio-oncologically one can expect an increase in the rate of cure in higher tumour stages by the use of interstitial brachycurie therapy, intraoperative radiotherapy, hyperthermia and the employment of radiosensitisers of low toxicity. Close interdisciplinary cooperation is essential for achieving the best possible success of treatment.
放射肿瘤学在头颈部肿瘤的治疗理念中占据重要地位。若在早期应用,单纯放疗就能取得极佳的缓解率和治愈率,且美容及功能效果良好。晚期肿瘤则需要采用包括手术、放疗和化疗在内的综合治疗模式。放疗结果显示与靶区所应用的剂量密切相关。该剂量取决于肿瘤的组织学类型、位置、大小以及淋巴结受累程度。从放射肿瘤学角度来看,通过应用间质近距离放疗、术中放疗、热疗以及使用低毒性放射增敏剂,有望提高较高肿瘤分期的治愈率。紧密的多学科合作对于实现最佳治疗效果至关重要。