Joshi Nidhi, Mathew Sylvia, George John V, Hegde Swaroop, Bhandi Shilpa, Madhu K S
Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, M S Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
J Conserv Dent. 2016 Jul-Aug;19(4):301-5. doi: 10.4103/0972-0707.186454.
Alleviating pain is of utmost importance when treating patients with endodontic pain.
To compare and evaluate the efficacy of two modes of delivery of pretreatment Piroxicam (Dolonex(®), Pfizer) for the management of postendodontic pain.
Sixty-six patients with symptomatic irreversible pulpitis were randomly divided into three groups of 22 subjects Group I - control group, no pharmacological intervention, Group II - patients received pretreatment oral Piroxicam (40 mg), Group III - patients received pretreatment intraligamentary injections totaling 0.4 mL of Piroxicam. Single visit endodontic therapy was performed by a single endodontist. Visual analogue scale was used to record pain before treatment and 4, 8, 12, 24, and 48 h postoperatively. Mann-Whitney U-test and Kruskal-Wallis tests were used to analyze the data.
The patients in Groups II and III perceived less postendodontic pain as compared to Group I (P < 0.05), at all the time intervals. At 12, 24, and 48 h, pain experience in patients of Group III was significantly less.
Intraligamentary mode of delivery of Piroxicam was more efficacious.
在治疗患有牙髓疼痛的患者时，减轻疼痛至关重要。
比较和评估两种预处理吡罗昔康（多乐士（®），辉瑞公司）给药方式对根管治疗后疼痛管理的疗效。
66例有症状的不可逆性牙髓炎患者被随机分为三组，每组22例。第一组为对照组，不进行药物干预；第二组患者接受口服吡罗昔康预处理（40毫克）；第三组患者接受总计0.4毫升吡罗昔康的韧带内注射预处理。由一名牙髓病医生进行单次就诊根管治疗。使用视觉模拟量表记录治疗前以及术后4、8、12、24和小时的疼痛情况。采用曼 - 惠特尼U检验和克鲁斯卡尔 - 沃利斯检验分析数据。
在所有时间间隔，第二组和第三组患者的根管治疗后疼痛均比第一组减轻（P < 0.05）。在12、24和48小时，第三组患者的疼痛感受明显减轻。
吡罗昔康的韧带内给药方式更有效。
