Oladejo Omolade, Allen Kristen, Amin Avnika, Frew Paula M, Bednarczyk Robert A, Omer Saad B
Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30022, USA.
Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30022, USA; Emory University, Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA.
Vaccine. 2016 Sep 22;34(41):4964-4968. doi: 10.1016/j.vaccine.2016.08.046. Epub 2016 Aug 23.
There is a need to develop a standardized tool to aid in identifying, measuring and classifying the unique needs of vaccine-hesitant parents (VHPs). This will also assist in designing tailored interventions to address these needs. The Parental Attitude about Childhood Vaccines (PACV) short scale developed by Opel et al., and the Gust et al. vaccine acceptance categories have been acknowledged as potentially useful tools to measure parental vaccine hesitancy. The PACV short scale requires further validation. In our study, we evaluated how the Gust et al. vaccine acceptance categories correspond with the PACV short scale.
As part of a larger study on vaccine attitudes, using the PACV short scale and Gust et al. vaccine acceptance categories, we assessed the correlation between the two measures using Spearman correlation coefficient, and the association between the two measures using the Cochran-Mantel-Haentszel test of association. We used logistic regression modelling to compare the association between a child's up-to-date immunization status and (a) PACV short scale and (b) Gust et al. vaccine acceptance categories.
The PACV short scale and Gust et al. vaccine acceptance categories were positively correlated (r=0.6, df=198, p<0.05), and the Cochran-Mantel-Haentszel test of association yielded a statistically significant association (p<0.05). The two scales similarly predicted children's up-to-date immunization status for all recommended childhood vaccines.
The ability of the PACV short scale to identify and classify parental vaccine hesitancy is similar to classification using Gust et al. vaccine acceptance categories, and both measure linear entities. The PACV short scale is recommended for screening parents at their first pediatric visit because it is easier to administer. A clearer understanding of how to classify parental vaccine hesitancy can be used to design tailored interventions based on these classifications, to address their specific needs.
需要开发一种标准化工具，以帮助识别、衡量和分类疫苗犹豫家长（VHP）的独特需求。这也将有助于设计针对性的干预措施来满足这些需求。Opel等人开发的《儿童疫苗家长态度》（PACV）简表以及Gust等人的疫苗接受类别已被认为是衡量家长疫苗犹豫的潜在有用工具。PACV简表需要进一步验证。在我们的研究中，我们评估了Gust等人的疫苗接受类别与PACV简表的对应情况。
作为一项关于疫苗态度的更大规模研究的一部分，我们使用PACV简表和Gust等人的疫苗接受类别，通过Spearman相关系数评估两种测量方法之间的相关性，并使用Cochran-Mantel-Haentszel关联检验评估两种测量方法之间的关联性。我们使用逻辑回归模型比较儿童的最新免疫状况与（a）PACV简表和（b）Gust等人的疫苗接受类别之间的关联。
PACV简表与Gust等人的疫苗接受类别呈正相关（r = 0.6，自由度 = 198，p < 0.05），Cochran-Mantel-Haentszel关联检验产生了具有统计学意义的关联（p < 0.05）。两种量表对所有推荐的儿童疫苗预测儿童最新免疫状况的方式相似。
PACV简表识别和分类家长疫苗犹豫的能力与使用Gust等人的疫苗接受类别进行分类的能力相似，且两者均测量线性实体。建议在家长首次儿科就诊时使用PACV简表进行筛查，因为它更易于实施。更清楚地了解如何对家长的疫苗犹豫进行分类，可用于根据这些分类设计针对性的干预措施，以满足他们的特定需求。
