Ardakani Jalal Vahedian, Mehrjardi Ali Zare, Wadji Massoud Baghai, Saraee Amir
Firoozgar General Hospital, Iran University of Medical Sciences, Tehran, Iran.
Indian J Surg. 2016 Aug;78(4):318-20. doi: 10.1007/s12262-015-1403-8. Epub 2015 Nov 13.
Desmoid tumors are locally aggressive and non-metastatic neoplasms with a high rate of recurrence. Desmoid tumors of the pancreas are, however, very rare, and only a few cases have been reported in the literature. This paper reports an anecdotal case of a diffuse pancreatic desmoid tumor with the involvement of the pancreatic head, body, and-partially-tail. The patient underwent the Whipple procedure and subtotal pancreatectomy. Histopathological assessment showed that the tissues were partly positive for smooth muscle actin, but not for S100 or PanCK. The Ki67 index of the cells was only 1 %. Unfortunately, the patient died on the 10th postoperative day due to massive upper gastrointestinal bleeding.
硬纤维瘤是具有高复发率的局部侵袭性非转移性肿瘤。然而，胰腺硬纤维瘤非常罕见，文献中仅报道了少数病例。本文报告了一例累及胰头、胰体及部分胰尾的弥漫性胰腺硬纤维瘤的罕见病例。患者接受了惠普尔手术及胰腺次全切除术。组织病理学评估显示，组织平滑肌肌动蛋白部分呈阳性，但S100或细胞角蛋白全谱（PanCK）呈阴性。细胞的Ki67指数仅为1%。不幸的是，患者术后第10天因大量上消化道出血死亡。
