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腹部手术术后谵妄的危险因素:腹部手术术后谵妄风险评分的建议

Risk Factors for Postoperative Delirium in Abdominal Surgery: A Proposal of a Postoperative Delirium Risk Score in Abdominal Surgery.

作者信息

Miyagawa Yasuhiro, Yokoyama Yukihiro, Fukuzawa Shota, Fukata Shinji, Ando Masahiko, Kawamura Takashi, Yamada Kiyofumi, Nagino Masato

机构信息

Department of Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya, Japan.

出版信息

Dig Surg. 2017;34(2):95-102. doi: 10.1159/000449044. Epub 2016 Aug 27.

Abstract

BACKGROUND/AIMS: Despite the presence of several diagnosis scales for delirium, no prediction scale that is specific for postoperative delirium after abdominal surgery is available. We sought to create a novel delirium prediction system that is specific for abdominal surgery.

METHODS

This study included 213 consecutive patients who required management in the surgical ICU following abdominal surgery. The Neelon and Champagne (NEECHAM) Confusion score was monitored throughout the postoperative course and patients with low NEECHAM score (≤26) were diagnosed as having delirium.

RESULTS

Seventy-three patients (34%) were categorized in the delirium group. Multivariate analyses indicated that an age >70 years, hypertension, those undergoing hepatopancreatobiliary or upper gastrointestinal surgeries, a serum albumin level <2.5 g/dl on postoperative day (POD) 3 or 5 and a ≥6 mEq/l gap in the serum sodium level between the preoperative value and that on POD 3 were independently associated with a low NEECHAM score (≤26). When the presence of each risk was counted as 1 point, 21 patients had ≥4 points and 15 of them (71%) had low NEECHAM score.

CONCLUSION

The scoring system combining multiple risk factors may be useful for predicting patients with an elevated risk for postoperative delirium after abdominal surgery.

摘要

背景/目的:尽管存在多种谵妄诊断量表,但尚无专门针对腹部手术后谵妄的预测量表。我们试图创建一种针对腹部手术的新型谵妄预测系统。

方法

本研究纳入了213例腹部手术后需要在外科重症监护病房进行管理的连续患者。在术后全过程监测Neelon和香槟(NEECHAM)意识模糊评分,NEECHAM评分低(≤26分)的患者被诊断为谵妄。

结果

73例患者(34%)被归类为谵妄组。多因素分析表明,年龄>70岁、高血压、接受肝胰胆或上消化道手术、术后第3天或第5天血清白蛋白水平<2.5 g/dl以及术前值与术后第3天血清钠水平差距≥6 mEq/l与低NEECHAM评分(≤26分)独立相关。当每种风险因素存在计为1分时,21例患者有≥4分,其中15例(71%)NEECHAM评分低。

结论

结合多种风险因素的评分系统可能有助于预测腹部手术后谵妄风险升高的患者。

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