Ferraro S, Fazio S, Santomauro M, De Magistris L, Cianfrani M, Saccà L
Cardiologia. 1989 Apr;34(4):327-31.
We divided 51 patients (Group C) with stable effort angina into 2 groups: Group A of 30 patients without previous myocardial infarction, Group B of 21 patients with previous myocardial infarction. The aim of this study was to test the relation between some ECG signs of ischemia and coronary artery disease (CAD) severity and to propose a new simple angiographic score of CAD. The patients, after a pharmacological wash-out period, were submitted to a treadmill effort test and to a coronarography. Stenoses were quantified using a score system recently proposed in the literature and a new simple score obtained summing the coronary stenosis in percent. Significant correlations between the time to the onset of ischemia (TSI) and the recovery time (TR) with the CAD severity in Groups A, B, and C using both scores were observed. The total stress time and the new index obtained summing the total effort time and the time to the onset of ischemia were related to the severity of CAD in Groups A and C using both scores. The multivariate discriminant analysis suggested that the TSI is the most sensitive variable to predict CAD severity in our patients. A good correlation between the 2 scores was also observed.
我们将51例稳定型劳力性心绞痛患者(C组)分为两组:A组30例,无既往心肌梗死病史;B组21例,有既往心肌梗死病史。本研究的目的是检验一些缺血性心电图征象与冠状动脉疾病(CAD)严重程度之间的关系,并提出一种新的简单的CAD血管造影评分系统。患者在经过药物洗脱期后,接受平板运动试验和冠状动脉造影。使用文献中最近提出的评分系统对狭窄程度进行量化,并通过将冠状动脉狭窄百分比相加得到一个新的简单评分。在A、B和C组中,使用这两种评分方法均观察到缺血发作时间(TSI)和恢复时间(TR)与CAD严重程度之间存在显著相关性。使用这两种评分方法,总应激时间以及将总运动时间和缺血发作时间相加得到的新指标与A组和C组的CAD严重程度相关。多变量判别分析表明,TSI是预测我们患者CAD严重程度最敏感的变量。两种评分之间也观察到良好的相关性。