Weber H, Schmitz L
Department of Paediatric Cardiology, University of Goettingen, F.R.G.
Eur Heart J. 1989 May;10(5):388-99. doi: 10.1093/oxfordjournals.eurheartj.a059501.
Catheter ablation of an accessory atrioventricular pathway was attempted in six patients with recurrent tachyarrhythmias resistant to medication (four to five trials). Localization of the accessory pathway was performed by potential recordings with an electrode catheter from the region of the tricuspid and mitral valve rings during orthodromic supraventricular tachycardia (n = 4), during sinus rhythm (n = 1), and during ventricular pacing (n = 1). Using this mapping technique, the site of earliest atrial or ventricular activation through the accessory pathway was localized in the anterior septal (n = 2), right free wall (n = 2), posterior septal (n = 2), or left free wall (n = 1) region of the atrioventricular valve rings. The shortest ventriculo-atrial (VA) and atrio-ventricular (AV) intervals measured in the local electrograms ranged from VA = 45-70 ms, and AV = 45-65 ms, respectively. The accessory pathway responsible for the arrhythmia demonstrated exclusive retrograde (n = 4) or bidirectional (n = 2) conduction properties. A total of 13 direct-current transcatheter shocks (one to three per patient) of 20-200 J each were aimed at the site of the accessory pathway. Thereby, conduction through the accessory pathway was abolished (n = 5) or modified (n = 1) and the patients were freed from their syncope and disabling arrhythmias (follow-up: 4.6-5.9 years). The procedure was well tolerated without complications. Mapping-guided catheter ablation of accessory pathways is an effective treatment of refractory supraventricular tachyarrhythmias in selected patients.
对6例对药物治疗无效(进行了4至5次试验)的复发性快速性心律失常患者尝试进行房室旁路导管消融术。在顺向性室上性心动过速期间(n = 4)、窦性心律期间(n = 1)和心室起搏期间(n = 1),使用电极导管从三尖瓣和二尖瓣环区域进行电位记录,以定位旁路。使用这种标测技术,通过旁路最早的心房或心室激动部位定位于房室瓣环的前间隔(n = 2)、右游离壁(n = 2)、后间隔(n = 2)或左游离壁(n = 1)区域。局部心电图测量的最短心室 - 心房(VA)和心房 - 心室(AV)间期分别为VA = 45 - 70毫秒和AV = 45 - 65毫秒。导致心律失常的旁路表现出单纯逆向(n = 4)或双向(n = 2)传导特性。总共对旁路部位进行了13次20 - 200焦耳的直流经导管电击(每位患者1至3次)。从而,旁路传导被阻断(n = 5)或改变(n = 1),患者摆脱了晕厥和致残性心律失常(随访:4.6 - 5.9年)。该操作耐受性良好,无并发症。标测引导下的旁路导管消融术是治疗特定患者难治性室上性快速性心律失常的有效方法。