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膀胱和前列腺超声形态学能否用于检测有症状的良性前列腺增生患者的膀胱出口梗阻?

Can Bladder and Prostate Sonomorphology Be Used for Detecting Bladder Outlet Obstruction in Patients With Symptomatic Benign Prostatic Hyperplasia?

作者信息

Ahmed Abul-Fotouh, Bedewi Mohamed

机构信息

Department of Urology, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia; Department of Urology, Al-Azhar University, Cairo, Egypt.

Department of Diagnostic Radiology, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.

出版信息

Urology. 2016 Dec;98:126-131. doi: 10.1016/j.urology.2016.08.033. Epub 2016 Aug 31.

Abstract

OBJECTIVE

To investigate the accuracy of the bladder and prostate sonomorphologic parameters for the diagnosis of bladder outlet obstruction (BOO) in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH).

PATIENTS AND METHODS

First-visit men, aged ≥ 50 years, with LUTS/BPH were prospectively enrolled. Added to the initial basic evaluation, all patients underwent pelvic ultrasonography and pressure flow study. The pressure flow study was used as a reference standard for BOO, and according to its results, patients were divided into BOO and non-BOO groups. The sonomorphologic findings were compared between both groups, and the diagnostic accuracy of the significant parameters was determined.

RESULTS

In total, 157 patients were included. Of these, 48 (30.57%) had BOO and 109 (69.43%) did not. Bladder wall thickness (BWT), ultrasound estimated bladder weight (UEBW), and intravesical prostatic protrusion (IPP) were the sonomorphologic parameters that differed significantly between both groups (P < .001). By receiver operating characteristic curve analysis, the optimal cutoff values distinguishing patients with BOO were BWT of 3.7 mm (area under the curve [AUC]: 0.940), UEBW of 31.5 g (AUC: 0.835), and IPP of 10.9 mm (AUC: 0.874). The sensitivity, specificity, and accuracy of BWT, UEBW, and IPP were 95.00%, 90.91%, and 93.55%; 75.44, 57.97%, and 65.62%; and 87.90%, 76.43%, and 82.17%, respectively.

CONCLUSION

BWT, UEBW, and IPP measurements can be used to detect BOO in LUTS/BPH patients. The simple estimation of these sonomorphologic parameters by suprapubic approach makes these measurements potentially suitable methods to judge BOO noninvasively during the routine clinical evaluation of BPH.

摘要

目的

探讨膀胱和前列腺超声形态学参数对下尿路症状(LUTS)/良性前列腺增生(BPH)患者膀胱出口梗阻(BOO)诊断的准确性。

患者与方法

前瞻性纳入年龄≥50岁的初诊LUTS/BPH男性患者。在初始基础评估之外,所有患者均接受盆腔超声检查和压力流研究。压力流研究用作BOO的参考标准,并根据其结果将患者分为BOO组和非BOO组。比较两组的超声形态学表现,确定显著参数的诊断准确性。

结果

共纳入157例患者。其中,48例(30.57%)有BOO,109例(69.43%)无BOO。膀胱壁厚度(BWT)、超声估计膀胱重量(UEBW)和膀胱内前列腺突入(IPP)是两组间有显著差异的超声形态学参数(P<0.001)。通过受试者工作特征曲线分析,区分BOO患者的最佳截断值为:BWT为3.7mm(曲线下面积[AUC]:0.940),UEBW为31.5g(AUC:0.835),IPP为10.9mm(AUC:0.874)。BWT、UEBW和IPP的敏感性、特异性和准确性分别为95.00%、90.91%和93.55%;75.44%、57.97%和65.62%;以及87.90%、76.43%和82.17%。

结论

BWT、UEBW和IPP测量可用于检测LUTS/BPH患者的BOO。经耻骨上途径对这些超声形态学参数进行简单估计,使这些测量有可能成为在BPH常规临床评估中无创判断BOO的合适方法。

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