Shustova N Ia, Dik I G, Nedoshivin V P, Levtov V A
Fiziol Zh SSSR Im I M Sechenova. 1989 Apr;75(4):493-507.
In 18 anesthetized cats, 60-sec occlusion of the m. gastrocnemius artery entailed a decrease in the muscle blood supply by 15-20 ml of the blood volume in the vessels whereas the post-occlusion increase in the blood flow restored the blood volume with 45% excess. The intravascular accumulation of the blood exerting a moderating effect upon the venous return while preserving the increased arterial inflow, can be regarded as an automatic way of limiting the hemodynamic excitation due to the postocclusion shifts and involved in systemic circulation. Papaverin interacts with the blood volume restoration and leads to insufficient restoration in the postocclusion period. This suggests that the postocclusion excessive restoration of the blood volume in muscle, as observed in control animals, can be due to an active vasodilatation of the capacitance portion of the intraorgan vascular bed.
在18只麻醉猫中,对腓肠肌动脉进行60秒的阻断会导致肌肉血液供应减少,血管内血容量减少15 - 20毫升,而阻断后血流增加会使血容量恢复且超出45%。血管内血液的积聚在保持动脉流入增加的同时,对静脉回流起到调节作用,可被视为一种自动限制因阻断后血流变化而引起的血流动力学兴奋并参与体循环的方式。罂粟碱与血容量恢复相互作用,导致阻断后时期恢复不足。这表明,在对照动物中观察到的肌肉血容量阻断后过度恢复,可能是由于器官内血管床容量部分的主动血管舒张所致。