• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[膝下病变的治疗:拓展血管外科手术的界限]

[Treatment of below the knee lesions: Broadening the limits of vascular surgery].

作者信息

Caradu C, Battut A S, Gonthier C, Midy D, Ducasse E

机构信息

Service de chirurgie vasculaire, université de Bordeaux, hôpital Pellegrin, place Amélie-Raba-Léon, 33000 Bordeaux, France.

Service de chirurgie vasculaire, université de Bordeaux, hôpital Pellegrin, place Amélie-Raba-Léon, 33000 Bordeaux, France.

出版信息

J Mal Vasc. 2016 Dec;41(6):378-382. doi: 10.1016/j.jmv.2016.07.006. Epub 2016 Sep 2.

DOI:10.1016/j.jmv.2016.07.006
PMID:27594571
Abstract

One third of patients with critical limb ischemia (CLI) has below the knee lesions and requires a restoration of direct blood flow into the foot. However, many of these patients are ineligible for open surgery. The primary goals thus become pain relief and limb salvage over patency. The angiosome concept helps determine the target artery to treat in priority. The endovascular approach has decreased morbidity and mortality rates compared to distal bypass surgery; while subintimal retrograde, trans-collateral and loop techniques push the limits of open surgery by reopening the plantar arch, thereby improving run-off. Early restenosis phenomena after angioplasty have been improved by the use of - limus drug eluting balloons and balloon expandable stents in case of flow limiting dissection or recoil with increased limb salvage rates. Moreover, drug-eluting stents have been proposed, and allow a reduction in reintervention and in-stent restenosis rates in short lesions; however, results on amputation rates or survival are limited. Vessel preparation is a key to overcoming some current limitations, including atherectomy, which increases technical success rates and reduces restenosis rates, especially in calcified lesions, chronic total occlusions and restenosis. These advanced techniques in distal endovascular revascularization have revolutionized limb salvage and support the interest of an endovascular first approach in CLI treatment.

摘要

三分之一的严重下肢缺血(CLI)患者存在膝下病变,需要恢复足部的直接血流。然而,这些患者中的许多人不适合进行开放手术。因此,主要目标变成了缓解疼痛和挽救肢体而非维持血管通畅。血管区域概念有助于确定优先治疗的目标动脉。与远端旁路手术相比,血管内治疗方法降低了发病率和死亡率;而内膜下逆行、经侧支和襻技术通过重新开通足底弓突破了开放手术的极限,从而改善了血流。血管成形术后的早期再狭窄现象通过使用西罗莫司药物洗脱球囊以及在出现血流受限的夹层或回缩时使用球囊扩张支架得到改善,肢体挽救率有所提高。此外,药物洗脱支架也已被提出,可降低短病变的再次干预率和支架内再狭窄率;然而,关于截肢率或生存率的结果有限。血管准备是克服当前一些局限性的关键,包括旋切术,它可提高技术成功率并降低再狭窄率,尤其是在钙化病变、慢性完全闭塞和再狭窄的情况下。这些远端血管内血运重建的先进技术彻底改变了肢体挽救的局面,并支持在CLI治疗中优先采用血管内治疗方法。

相似文献

1
[Treatment of below the knee lesions: Broadening the limits of vascular surgery].[膝下病变的治疗:拓展血管外科手术的界限]
J Mal Vasc. 2016 Dec;41(6):378-382. doi: 10.1016/j.jmv.2016.07.006. Epub 2016 Sep 2.
2
Drug-eluting balloon in peripheral intervention for below the knee angioplasty evaluation (DEBATE-BTK): a randomized trial in diabetic patients with critical limb ischemia.药物涂层球囊在膝下血管成形术评估中的外周介入治疗(DEBATE-BTK):糖尿病合并严重肢体缺血患者的随机试验。
Circulation. 2013 Aug 6;128(6):615-21. doi: 10.1161/CIRCULATIONAHA.113.001811.
3
Innovations in the Endovascular Management of Critical Limb Ischemia: Retrograde Tibiopedal Access and Advanced Percutaneous Techniques.严重肢体缺血的血管内治疗创新:逆行胫足部入路及先进的经皮技术
Curr Cardiol Rep. 2017 Aug;19(8):68. doi: 10.1007/s11886-017-0879-1.
4
Six-year multicenter experience of standard endovascular treatment of critical limb ischemia in the era of drug-eluting devices.药物洗脱装置时代严重肢体缺血标准血管内治疗的六年多中心经验
J Cardiovasc Surg (Torino). 2018 Oct;59(5):707-715. doi: 10.23736/S0021-9509.16.09737-8. Epub 2016 Nov 23.
5
Infrapopliteal angioplasty for critical limb ischemia: relation of TransAtlantic InterSociety Consensus class to outcome in 176 limbs.下肢动脉成形术治疗严重肢体缺血:176例肢体的跨大西洋跨学会共识分类与预后的关系
J Vasc Surg. 2008 Jul;48(1):128-36. doi: 10.1016/j.jvs.2008.02.027. Epub 2008 May 23.
6
Impact of femoropopliteal endovascular interventions on subsequent open bypass.股腘动脉血管腔内介入治疗对后续开放旁路手术的影响。
J Vasc Surg. 2016 Sep;64(3):623-8. doi: 10.1016/j.jvs.2016.03.467. Epub 2016 Jun 8.
7
"Ranger BTK" a Prospective Single-Centre Cohort Study on a New Drug-Coated Balloon for Below the Knee Lesions in Patients with Critical Limb Ischemia.“Ranger BTK”:一种新型药物涂层球囊治疗严重肢体缺血患者膝下病变的前瞻性单中心队列研究。
Cardiovasc Intervent Radiol. 2021 Jul;44(7):1017-1027. doi: 10.1007/s00270-021-02833-1. Epub 2021 May 4.
8
Endovascular therapy for critical limb ischemia.严重肢体缺血的血管内治疗
Expert Rev Cardiovasc Ther. 2015 Apr;13(4):429-44. doi: 10.1586/14779072.2015.1019472. Epub 2015 Mar 2.
9
A systematic review and meta-analysis of revascularization outcomes of infrainguinal chronic limb-threatening ischemia.系统评价和荟萃分析显示,血运重建治疗下肢慢性肢体威胁性缺血的效果。
Eur J Vasc Endovasc Surg. 2019 Jul;58(1S):S110-S119. doi: 10.1016/j.ejvs.2019.04.013. Epub 2019 Jun 17.
10
A systematic review and meta-analysis of revascularization outcomes of infrainguinal chronic limb-threatening ischemia.下肢慢性肢体威胁性缺血血运重建结局的系统评价和荟萃分析。
J Vasc Surg. 2018 Aug;68(2):624-633. doi: 10.1016/j.jvs.2018.01.066. Epub 2018 May 24.