金（I）催化的醇与丙二烯的多米诺偶联反应可实现高度取代茚的合成。
A Gold(I)-Catalyzed Domino Coupling of Alcohols with Allenes Enables the Synthesis of Highly Substituted Indenes.
作者信息
Preinfalk Alexander, Misale Antonio, Maulide Nuno
机构信息
Faculty of Chemistry, Institute of Organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
出版信息
Chemistry. 2016 Oct 4;22(41):14471-4. doi: 10.1002/chem.201603154. Epub 2016 Sep 6.
PMID:27596096
Abstract
The reaction of aryl-substituted allenes with alcohols under gold catalysis led to highly substituted indenes in good yields, with low catalyst loading and under mild conditions. During this domino transformation, two C-C bonds are formed with water as the only byproduct.
摘要
在金催化下，芳基取代的丙二烯与醇反应，能以良好的产率、低催化剂用量且在温和条件下生成高度取代的茚。在这一多米诺转化过程中，形成了两个碳 - 碳键，且仅产生水作为副产物。
Zotero 插件