芬兰人群中转铁蛋白C亚型的频率。

Transferrin C subtype frequencies in the Finnish population.

作者信息

Tenkanen H, Metso J, Lukka M

机构信息

National Public Health Institute, Helsinki, Finland.

出版信息

Hum Hered. 1989;39(1):55-7. doi: 10.1159/000153834.

DOI:10.1159/000153834

PMID:2759627

Abstract

Transferrin (Tf) C subtypes were determined in 419 unrelated adult Finns. The calculated gene frequencies were C1 = 0.738, C2 = 0.097 and C3 = 0.133. The Tf phenotypes in 150 mother-child pairs were in accordance with autosomal codominant inheritance. This material included a rare TfC allele product in three individuals, apparently the same in all cases.

摘要

在419名无亲缘关系的成年芬兰人中测定了转铁蛋白（Tf）C亚型。计算得到的基因频率为C1 = 0.738，C2 = 0.097，C3 = 0.133。150对母婴的Tf表型符合常染色体共显性遗传。该样本中有三名个体带有一种罕见的TfC等位基因产物，在所有病例中似乎相同。