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门诊使用氟哌啶醇成功治疗疑似大麻素呕吐综合征

Successful Treatment of Suspected Cannabinoid Hyperemesis Syndrome Using Haloperidol in the Outpatient Setting.

作者信息

Jones Jennifer L, Abernathy Karen E

机构信息

Departments of Psychiatry and Internal Medicine, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA.

Department of Medicine, Division of General Internal Medicine and Geriatrics, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA.

出版信息

Case Rep Psychiatry. 2016;2016:3614053. doi: 10.1155/2016/3614053. Epub 2016 Aug 11.

Abstract

Chronic use of cannabis can result in a syndrome of hyperemesis characterized by cyclical vomiting without any other identifiable causes. Cannabinoid hyperemesis syndrome (CHS) is seldom responsive to traditional antiemetic therapies. Despite frequent nausea and vomiting, patients may be reluctant to discontinue use of cannabis. We report a case of severe, refractory CHS with complete resolution of nausea and vomiting after treatment with haloperidol in the outpatient setting. After review of the literature, we believe this is the first reported successful outpatient treatment of CHS and suggests a potential treatment for refractory patients.

摘要

长期使用大麻可导致一种以周期性呕吐为特征的呕吐综合征,且无任何其他可识别的病因。大麻素呕吐综合征(CHS)对传统的止吐疗法很少有反应。尽管频繁出现恶心和呕吐,但患者可能不愿停止使用大麻。我们报告一例严重的难治性CHS病例,在门诊环境中使用氟哌啶醇治疗后,恶心和呕吐完全缓解。在查阅文献后,我们认为这是首次报道的门诊成功治疗CHS的病例,并提示为难治性患者提供了一种潜在的治疗方法。

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