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强直性脊柱炎与1型神经纤维瘤病并存

Coexistence of Ankylosing Spondylitis and Neurofibromatosis Type 1.

作者信息

Gundogdu Baris, Yolbas Servet, Yildirim Ahmet, Gonen Murat, Koca Suleyman Serdar

机构信息

Department of Rheumatology, Faculty of Medicine, Firat University, 23200 Elazig, Turkey.

Department of Neurology, Faculty of Medicine, Firat University, 23200 Elazig, Turkey.

出版信息

Case Rep Rheumatol. 2016;2016:4039801. doi: 10.1155/2016/4039801. Epub 2016 Aug 14.

Abstract

Ankylosing spondylitis (AS) is a systemic disease primarily characterized by the inflammation of sacroiliac joints and axial skeleton. Neurofibromatosis type 1 (NF1) is a multisystem genetic disease which is characterized by cutaneous findings, most importantly café-au-lait spots and axillary freckling, by skeletal dysplasia, and by the growth of both benign and malignant nervous system neoplasms, most notably benign neurofibromas. In this case report, we present a 43-year-old male with AS and NF1.

摘要

强直性脊柱炎(AS)是一种全身性疾病,主要特征为骶髂关节和中轴骨骼的炎症。1型神经纤维瘤病(NF1)是一种多系统遗传病,其特征包括皮肤表现,最重要的是牛奶咖啡斑和腋窝雀斑,骨骼发育异常,以及良性和恶性神经系统肿瘤的生长,最显著的是良性神经纤维瘤。在本病例报告中,我们介绍了一名患有AS和NF1的43岁男性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/572f/5002286/44b529cd2d69/CRIRH2016-4039801.001.jpg

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