Kleinwechter Helmut, Demandt Norbert
Dtsch Med Wochenschr. 2016 Sep;141(18):1296-303. doi: 10.1055/s-0042-110555. Epub 2016 Sep 6.
In Germany in 5.5% of all births diabetes is registered. In patients with type 1 and type 2 diabetes planning pregnancy, preconception counseling, diabetologic care with optimized periconceptional metabolic control and folic acid supplementation are essential for good pregnancy outcome. Gestational diabetes (GDM) should be diagnosed timely and managed according to existing guidelines. GDM is treated with insulin in approximately 20%. In 1-2% of GDM cases a glucokinase gene mutation is present (MODY 2). Pregnancies after bariatric-metabolic surgery are increasing and show high risks.
在德国,所有出生婴儿中有5.5%被登记患有糖尿病。对于计划怀孕的1型和2型糖尿病患者,孕前咨询、优化孕期代谢控制的糖尿病护理以及补充叶酸对于良好的妊娠结局至关重要。妊娠期糖尿病(GDM)应及时诊断并按照现有指南进行管理。约20%的GDM患者使用胰岛素治疗。1%-2%的GDM病例存在葡萄糖激酶基因突变(MODY 2)。减肥代谢手术后的妊娠情况日益增多且风险较高。