Topographic determination of corneal asphericity as a function of age, gender, and refractive error.

The aim of the study is to evaluate corneal asphericity in three diameters of 5, 6, and 7 mm, and to assess the effect of age, refractive error, and gender on asphericity. The study included 500 healthy subjects with a mean ± SD age of 29.51 ± 11.53 years. All analyses were based on the right eyes of the patients. Topographic data were analyzed using Oculus Keratograph 4. Mean ± SD corneal asphericity values of the study population in 5, 6, and 7 mm diameters were -0.21 ± 0.11, -0.24 ± 0.10, and -0.27 ± 0.11, respectively. The anterior corneal surface asphericity showed no correlation with either age, gender, or refractive error. The corneal asphericity shows a tendency for an increase with diameter and asphericity does not have a significant correlation with any factors of age, gender, and refractive error.