Szulc Pawel, Duboeuf François, Chapurlat Roland
INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, Lyon, France.
INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, Lyon, France.
J Clin Densitom. 2017 Oct-Dec;20(4):472-479. doi: 10.1016/j.jocd.2016.08.003. Epub 2016 Sep 2.
Data on age-related differences in fat mass and distribution in men are scarce. We performed a cross-sectional analysis of age-related differences in fat distribution in men. In a cohort of 1133 men aged 20-87 yr, body composition was assessed using a Hologic Discovery A device. We assessed fat mass (FM) and FM indices adjusted for height. Interindividual variability was calculated as standard deviation, interquartile range, and difference between the 95th and 5th percentiles in 5-yr age groups. After adjustment for lifestyle factors, the FM and FM index of appendicular, gynoid, central, android, and subcutaneous abdominal compartments increased with age. Their variability did not vary with age. Visceral FM was 181% higher in men aged >80 yr compared to men aged 20-30 yr, and the variability increased with age. FM in the central, android, subcutaneous abdominal, and visceral compartments correlated with age significantly more strongly before the age of 70 than after this age. The relative differences between the elderly and younger men were greater for visceral FM than for subcutaneous (abdominal and appendicular) fat. The interindividual variability in visceral FM is higher in elderly men. The association between visceral FM and age is stronger before the age of 70.
关于男性脂肪量和分布的年龄相关差异的数据很少。我们对男性脂肪分布的年龄相关差异进行了横断面分析。在一个由1133名年龄在20 - 87岁的男性组成的队列中，使用Hologic Discovery A设备评估身体成分。我们评估了脂肪量（FM）和根据身高调整的FM指数。个体间变异性以标准差、四分位间距以及5岁年龄组中第95和第5百分位数之间的差异来计算。在对生活方式因素进行调整后，上肢、臀部、中心、腹部和皮下腹部区域的FM和FM指数随年龄增加。它们的变异性不随年龄变化。80岁以上男性的内脏FM比20 - 30岁男性高181%，且变异性随年龄增加。在70岁之前，中心、腹部、皮下腹部和内脏区域的FM与年龄的相关性显著强于70岁之后。老年男性与年轻男性在内脏FM方面的相对差异大于皮下（腹部和上肢）脂肪。老年男性内脏FM的个体间变异性更高。70岁之前，内脏FM与年龄的关联更强。
