Kaur Mandeep, Kumar Rakesh, Upendrabhai Deep Patel, Singh Inder Pal, Kaur Sanehdeep
Department of Zoology, Guru Nanak Dev University, Amritsar, Punjab, India.
Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, India.
Pest Manag Sci. 2017 May;73(5):1031-1038. doi: 10.1002/ps.4429. Epub 2016 Oct 27.
The use of botanical pesticides for protecting crops from insect pests has assumed greater importance all over the world owing to growing awareness of harmful effects of indiscriminate use of synthetic pesticides. Inula racemosa Hook. f. (Asteraceae), a medicinally important perennial herb, is rich in sesquiterpenes with many biological activities. The present studies were conducted with the objective to evaluate the sesquiterpenes isolated from I. racemosa for insecticidal activity against Spodoptera litura (F.).
Alantolactone and isoalantolactone isolated from I. racemosa exerted growth inhibitory effects on S. litura. Addition of both the sesquiterpenes to larval diet extended the development period and reduced pupation as well as adult emergence. The dietary utilisation experiments on third-instar larvae of S. litura revealed reduction in consumption and growth rates of larvae as well as efficiency of conversion of ingested and digested food owing to alantolactone and isoalantolactone.
The root extract of I. racemosa, which is rich in two sesquiterpenes, i.e. alantolactone and isoalantolactone, has the potential for management of S. litura. However, there is a need to understand the specific mechanism of action of these compounds. © 2016 Society of Chemical Industry.
由于人们越来越意识到滥用合成农药的有害影响，在全球范围内，使用植物性杀虫剂保护作物免受虫害变得越发重要。土木香（Inula racemosa Hook. f.，菊科）是一种具有重要药用价值的多年生草本植物，富含具有多种生物活性的倍半萜。本研究旨在评估从土木香中分离出的倍半萜对斜纹夜蛾（Spodoptera litura (F.)）的杀虫活性。
从土木香中分离出的阿兰内酯和异阿兰内酯对斜纹夜蛾具有生长抑制作用。将这两种倍半萜添加到幼虫饲料中会延长其发育时间，并减少化蛹和成虫羽化。对斜纹夜蛾三龄幼虫的饲料利用实验表明，由于阿兰内酯和异阿兰内酯的作用，幼虫的摄食量和生长速率以及摄取和消化食物的转化率均有所降低。
富含阿兰内酯和异阿兰内酯这两种倍半萜的土木香根提取物具有防治斜纹夜蛾的潜力。然而，有必要了解这些化合物的具体作用机制。© 2016化学工业协会。
