[对抗疟药物的耐药性]

[Resistance to the antimalarial drugs].

作者信息

Venanzi E, López-Vélez R

机构信息

Rogelio López-Vélez, Unidad de Referencia Nacional para Enfermedades Tropicales. Servicio de Enfermedades Infecciosas. Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.

出版信息

Rev Esp Quimioter. 2016 Sep;29 Suppl 1:72-5.

PMID:27608319

Abstract

Malaria is one of the most widespread infectious diseases around the world with 214 million cases and 438,000 deaths in 2015. In the early twentieth century it was described for the first time the resistance to quinine and, since then, drug resistance to antimalarial drugs has spread up to represent a global challenge in the fight and control of malaria. Understanding the mechanisms, geography and monitoring tools that we can act against resistance to antimalarial drugs is critical to prevent its expansion.

摘要

疟疾是全球最广泛传播的传染病之一，2015年有2.14亿病例，43.8万人死亡。20世纪初首次描述了对奎宁的耐药性，从那时起，对抗疟药物的耐药性不断蔓延，已成为疟疾防治中的一项全球性挑战。了解我们可以针对抗疟药物耐药性采取行动的机制、地域范围和监测工具，对于防止其蔓延至关重要。