Lee SeokHyun, Cho KwangHyun, Park MiNa, Choi TaeJung, Kim SiDong, Do ChangHee
Division of Animal and Dairy Science, Chungnam National University, Daejeon 34134, Korea.
National Institute of Animal Science, RDA, Cheonan, 31000, Korea.
Asian-Australas J Anim Sci. 2016 Nov;29(11):1530-1540. doi: 10.5713/ajas.16.0310. Epub 2016 Sep 9.
This study was conducted to estimate the genetic parameters of β-hydroxybutyrate (BHBA) and acetone concentration in milk by Fourier transform infrared spectroscopy along with test-day milk production traits including fat %, protein % and milk yield based on monthly samples of milk obtained as part of a routine milk recording program in Korea. Additionally, the feasibility of using such data in the official dairy cattle breeding system for selection of cows with low susceptibility of ketosis was evaluated. A total of 57,190 monthly test-day records for parities 1, 2, and 3 of 7,895 cows with pedigree information were collected from April 2012 to August 2014 from herds enrolled in the Korea Animal Improvement Association. Multi-trait random regression models were separately applied to estimate genetic parameters of test-day records for each parity. The model included fixed herd test-day effects, calving age and season effects, and random regressions for additive genetic and permanent environmental effects. Abundance of variation of acetone may provide a more sensitive indication of ketosis than many zero observations in concentration of milk BHBA. Heritabilities of milk BHBA levels ranged from 0.04 to 0.17 with a mean of 0.09 for the interval between 4 and 305 days in milk during three lactations. The average heritabilities for milk acetone concentration were 0.29, 0.29, and 0.22 for parities 1, 2, and 3, respectively. There was no clear genetic association of the concentration of two ketone bodies with three test-day milk production traits, even if some correlations among breeding values of the test-day records in this study were observed. These results suggest that genetic selection for low susceptibility of ketosis in early lactation is possible. Further, it is desirable for the breeding scheme of dairy cattle to include the records of milk acetone rather than the records of milk BHBA.
本研究旨在通过傅里叶变换红外光谱法，结合韩国常规牛奶记录计划中每月采集的牛奶样本的产奶日性状（包括乳脂率、乳蛋白率和产奶量），估计牛奶中β-羟基丁酸（BHBA）和丙酮浓度的遗传参数。此外，还评估了在官方奶牛育种系统中使用此类数据来选择酮病易感性低的奶牛的可行性。2012年4月至2014年8月，从韩国动物改良协会登记的牛群中收集了7895头有系谱信息的奶牛第1、2和3胎的57190条月度产奶日记录。多性状随机回归模型分别用于估计各胎次产奶日记录的遗传参数。该模型包括固定的牛群产奶日效应、产犊年龄和季节效应，以及加性遗传和永久环境效应的随机回归。丙酮含量的丰富变化可能比牛奶BHBA浓度中的许多零观测值更能敏感地指示酮病。在三个泌乳期的4至305天泌乳间隔内，牛奶BHBA水平的遗传力范围为0.04至0.17，平均为0.09。第1、2和3胎次牛奶丙酮浓度的平均遗传力分别为0.29、0.29和0.22。即使在本研究中观察到产奶日记录的育种值之间存在一些相关性，但两种酮体的浓度与三个产奶日产奶性状之间没有明显的遗传关联。这些结果表明，在泌乳早期对酮病低易感性进行遗传选择是可行的。此外，奶牛育种方案最好纳入牛奶丙酮记录而非牛奶BHBA记录。
