Benad A, Richter E
Klinik für Augenheilkunde des Bereiches Medizin, Wilhelm-Pieck-Universität Rostock.
Klin Monbl Augenheilkd. 1989 Jun;194(6):424-6. doi: 10.1055/s-2008-1046395.
The authors report on the results of therapy with 0.1% BVDU eye drops in a pilot study involving 80 patients suffering from stellate, dendritic, and geographic keratitis. Tolerance of this drug was very good. Healing occurred in 66 patients (82.5%) within 14 days. In these patients re-epithelialization was complete after an average of 5.4 days. In 13 patients (16.3%) the lesion took more than 14 days to heal (mean 18.2 days). The therapy must therefore be considered as having failed in these cases. In one patient (1.2%) the treatment had to be discontinued, as his condition deteriorated during treatment with BVDU.
作者报告了一项试点研究的结果,该研究使用0.1%的溴乙烯尿苷眼药水治疗80例患有星状、树枝状和地图状角膜炎的患者。这种药物的耐受性非常好。66例患者(82.5%)在14天内痊愈。这些患者平均在5.4天后上皮重新形成完成。13例患者(16.3%)病变愈合超过14天(平均18.2天)。因此,在这些病例中必须认为治疗失败。1例患者(1.2%)因在用溴乙烯尿苷治疗期间病情恶化而不得不停止治疗。