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乳腺韧带样型纤维瘤病:一例报告。

Desmoid-type fibromatosis of the breast: A case report.

作者信息

Bhat Deepa, Wear Vanessa, Weisenberg Elliot, Alvarado Rosalinda

出版信息

Breast Dis. 2016;36(4):149-152. doi: 10.3233/BD-160227.

Abstract

Desmoid-type fibromatosis of the breast (also referred to as desmoid tumor or aggressive fibromatosis) is exceedingly rare. Although it does not metastasize, desmoid-type fibromatosisis is frequently locally aggressive. Recurrence is common (up to 35%), even after presumed total excision of the primary tumor [1]. The breast is an unusual location for the development of this tumor, with relatively few cases reported in the literature. We report a case of desmoid-type fibromatosis in the breast in a 31-year-old female who presented with a four-month history of a palpable left breast mass. Her imaging was discordant, so she underwent surgical excision of the mass. Multiple positive margins were present. She underwent re-excision to the level of the sternum medially. Final pathology showed a focally positive posterior margin, without muscle or fascial involvement. The patient's case was discussed at the multidisciplinary tumor board conference and no further intervention was recommended. To our knowledge, this is the first case report in the literature in which negative margins were unable to be achieved for desmoid tumors of the breast operatively.

摘要

乳腺韧带样型纤维瘤病(也称为韧带样瘤或侵袭性纤维瘤病)极为罕见。尽管它不会发生转移,但韧带样型纤维瘤病通常具有局部侵袭性。复发很常见(高达35%),即使在假定原发肿瘤已完全切除之后[1]。乳腺是该肿瘤发生的不常见部位,文献报道的病例相对较少。我们报告一例31岁女性乳腺韧带样型纤维瘤病,该患者有可触及的左乳肿块,病史4个月。其影像学表现不一致,因此她接受了肿块的手术切除。存在多个切缘阳性。她接受了再次切除,内侧至胸骨水平。最终病理显示后切缘局部阳性,无肌肉或筋膜受累。该患者的病例在多学科肿瘤委员会会议上进行了讨论,不建议进一步干预。据我们所知,这是文献中首例关于乳腺韧带样瘤手术无法实现切缘阴性的病例报告。

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