Silenko O V
Kosm Biol Aviakosm Med. 1989 May-Jun;23(3):34-8.
Cardiovascular responses of healthy male subjects to static loading in the horizontal, orthostatic and antiorthostatic positions were investigated. The body position was found to affect significantly both the sign and magnitude of circulation parameters. It was also shown that static loading tolerance was lower in the orthostatic than in the antiorthostatic position. It was hypothesized that the complex mechanism of adaptation to static loading involves purely physical factors (obstruction of small arterial vessels and blood discharge from veins of the strained muscle), central, intermediate and local reflex mechanisms. Resistance vessels play a predominant role in limiting systemic arterial pressure in the orthostatic position. Of greated importance in the horizontal position is venous blood pooling limiting its return to the heart. Rearrangement in hemodynamics during static loading is accompanied by an increase in the effective coronary blood flow which is the greatest in the orthostatic position.
研究了健康男性受试者在水平位、直立位和反直立位进行静态负荷时的心血管反应。发现身体姿势对循环参数的正负和大小均有显著影响。还表明,直立位的静态负荷耐受性低于反直立位。据推测,适应静态负荷的复杂机制涉及纯粹的物理因素(小动脉血管阻塞和紧张肌肉静脉的血液排出)、中枢、中间和局部反射机制。阻力血管在限制直立位时的全身动脉压方面起主要作用。在水平位,静脉血液淤积限制其回流至心脏更为重要。静态负荷期间血液动力学的重新调整伴随着有效冠状动脉血流量的增加,这在直立位时最大。