Nagel J D, Kort W J, Varossieau F, McVie J G
Department of Experimental Therapy, Antoni van Leeuwenhoekhuis, Amsterdam, The Netherlands.
Lab Anim. 1989 Jul;23(3):197-9. doi: 10.1258/002367789780810527.
A new method of sampling ascitic fluid from rats over a period of at least 8 h in a reliable and easy way is described. The objective was to determine drug concentrations in ascitic fluid after intraperitoneal chemotherapy. Two silicon tubes were implanted into the abdominal cavity, one for drug administration and regulation of pressure, the other enabled ascitic fluid to be withdrawn.
本文描述了一种以可靠且简便的方式对大鼠腹水进行至少8小时采样的新方法。目的是测定腹腔化疗后腹水中的药物浓度。将两根硅胶管植入腹腔，一根用于给药和调节压力，另一根用于抽取腹水。
