肝内胆管癌合并直肠癌肝转移：一例报告

Intrahepatic cholangiocarcinoma coinciding with a liver metastasis from a rectal carcinoma: a case report.

作者信息

Akabane Shintaro, Ohira Masahiro, Kobayashi Tsuyoshi, Kuroda Shintaro, Tanimine Naoki, Shimizu Seiichi, Tahara Hiroyuki, Ide Kentaro, Ishiyama Kohei, Egi Hiroyuki, Tanabe Kazuaki, Sentani Kazuhiro, Yasui Wataru, Ohdan Hideki

机构信息

Department of Gastroenterological and Transplant Surgery, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

Department of Molecular Pathology, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

出版信息

Surg Case Rep. 2016 Dec;2(1):94. doi: 10.1186/s40792-016-0222-x. Epub 2016 Sep 9.

DOI:10.1186/s40792-016-0222-x

PMID:27612869

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5016489/

Abstract

BACKGROUND

We experience many cases of liver metastasis from colorectal cancer, but synchronous occurrence of intrahepatic cholangiocarcinoma (ICC) and liver metastasis from a rectal cancer is extremely rare. We herein report a case of ICC coinciding with a liver metastasis from a known rectal carcinoma.

CASE PRESENTATION

A 68-year-old man was referred to our hospital for investigation of multiple liver tumors. Total colonoscopy and computed tomography (CT) revealed a rectal carcinoma, coinciding with liver metastasis. He was planned to receive chemotherapy following rectal resection. During chemotherapy for the rectal cancer, one of the liver tumors gradually grew after first shrinking. The following hepatectomy revealed the presence of intrahepatic cholangiocarcinoma (ICC). Despite intensive chemotherapy for the ICC, he passed away 6 months after the hepatectomy.

CONCLUSIONS

We should also suspect the possibility of multiple primary cancers, even if the patient has a history of cancer that is likely to cause metastatic lesions. When simultaneous neoplasms are diagnosed, systematic treatment should be targeted to the tumor with the worst prognosis.

摘要