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儿童偏头痛:综述

Migraine in Children: A Review.

作者信息

Ahmed S, Tabassum S, Rahman S M, Akhter S, Rahman M M, Bayes F, Roy S

机构信息

Dr Sanjida Ahmed, Medical Officer, Institute of Pediatric Neuro-disorder and Autism (IPNA), Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh.

出版信息

Mymensingh Med J. 2016 Jul;25(3):589-96.

Abstract

Recurrent headache is common in children. Among them migraine is the most common disabling cause of primary headache. It causes serious disability in child's life and family. It causes negative impact on their quality of life. Clinical characteristic of migraine in children differ from adult. It may be shorter in duration and bifrontal or bitemporal in location in contrast to adult which is longer in duration and usually unilateral. It is less common before 3 years of age. Males are more affected before puberty. But after puberty females are predominantly affected. Intensity of pain is moderate to severe. There are some triggering factors. Positive family history usually present. Disability can be assessed by PedMIDAS scale in children and adolescents which is modified version of MIDAS scale for adult. Diagnosis of migraine usually clinical but evaluation should be done to exclude severe underlying secondary cause. Management consists of pharmacological and non pharmacological approach. Parental education, life style modification is the mainstay of management. Acute treatment consists of Acetaminophen, NSAIDs and Triptans. Among Triptans, Sumatriptan nasal spray is only found effective for children. Preventive therapy aims to decrease frequency and severity of headache. Flunarizine, Propranolol, Amitryptylline, Levetiracetam, Valproate, Topiramate are found effective in pediatric age group. Pediatrician should evaluate the child to exclude secondary cause of headache when indicated. They should have also proper knowledge and skills to manage a child having migraine to improve their quality of life and academic achievement.

摘要

复发性头痛在儿童中很常见。其中偏头痛是原发性头痛最常见的致残原因。它会给儿童的生活和家庭带来严重的残疾,对他们的生活质量产生负面影响。儿童偏头痛的临床特征与成人不同。与成人偏头痛持续时间较长且通常为单侧相比,儿童偏头痛的持续时间可能较短,且位于双侧额部或颞部。3岁前较少见。青春期前男性受影响更多。但青春期后女性受影响为主。疼痛强度为中度至重度。存在一些触发因素。通常有阳性家族史。儿童和青少年的残疾程度可通过PedMIDAS量表评估,该量表是成人MIDAS量表的修订版。偏头痛的诊断通常基于临床,但应进行评估以排除严重的潜在继发性病因。治疗包括药物治疗和非药物治疗。家长教育、生活方式改变是治疗的主要内容。急性治疗包括对乙酰氨基酚、非甾体抗炎药和曲坦类药物。在曲坦类药物中,仅舒马曲坦鼻喷雾剂对儿童有效。预防性治疗旨在降低头痛的频率和严重程度。氟桂利嗪、普萘洛尔、阿米替林、左乙拉西坦、丙戊酸盐、托吡酯在儿童年龄组中被发现有效。儿科医生应在有指征时评估儿童以排除头痛的继发性病因。他们还应具备管理偏头痛儿童的适当知识和技能,以提高他们的生活质量和学业成绩。

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