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[小细胞肺癌的放射治疗]

[Radiotherapy for small cell lung carcinoma].

作者信息

Pourel N

机构信息

Département de radiothérapie, institut Sainte-Catherine, 250, chemin de Baigne-Pieds, CS80005, 84918 Avignon cedex 9, France.

出版信息

Cancer Radiother. 2016 Oct;20(6-7):547-57. doi: 10.1016/j.canrad.2016.07.092. Epub 2016 Sep 7.

DOI:10.1016/j.canrad.2016.07.092
PMID:27614522
Abstract

Radiotherapy for small cell lung carcinoma has known significant improvements over the past 10 years especially through routine use of PET-CT in the initial work-up and contouring before treatment. Prophylactic cranial irradiation remains a standard of care for locally advanced disease and is a subject of controversy for metastatic disease. A new indication for thoracic radiotherapy may soon arise for metastatic disease, still confirmation studies are ongoing.

摘要

在过去10年中,小细胞肺癌的放射治疗有了显著改善,特别是通过在初始检查和治疗前轮廓勾画中常规使用PET-CT。预防性颅脑照射仍然是局部晚期疾病的标准治疗方法,对于转移性疾病则存在争议。针对转移性疾病,胸部放疗可能很快会出现新的适应证,不过相关验证研究仍在进行中。

相似文献

1
[Radiotherapy for small cell lung carcinoma].[小细胞肺癌的放射治疗]
Cancer Radiother. 2016 Oct;20(6-7):547-57. doi: 10.1016/j.canrad.2016.07.092. Epub 2016 Sep 7.
2
Radiotherapy in small-cell lung cancer: lessons learned and future directions.小细胞肺癌的放射治疗:经验教训与未来方向。
Int J Radiat Oncol Biol Phys. 2011 Mar 15;79(4):998-1003. doi: 10.1016/j.ijrobp.2010.10.039.
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[Radiotherapy for primary lung carcinoma].[原发性肺癌的放射治疗]
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Current Patterns of Care for Patients with Extensive-Stage SCLC: Survey of U.S. Radiation Oncologists on Their Recommendations Regarding Prophylactic Cranial Irradiation.广泛期小细胞肺癌患者的治疗现状:对美国放疗医师关于预防性颅脑照射推荐意见的调查。
J Thorac Oncol. 2016 Aug;11(8):1305-1310. doi: 10.1016/j.jtho.2016.04.031. Epub 2016 May 26.
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The Road Less Traveled: Should We Omit Prophylactic Cranial Irradiation for Patients With Small Cell Lung Cancer?《少有人走的路:我们是否应该为小细胞肺癌患者省略预防性颅脑照射?》
Clin Lung Cancer. 2018 Jul;19(4):289-293. doi: 10.1016/j.cllc.2018.03.006. Epub 2018 Mar 16.
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Utilization of prophylactic cranial irradiation in patients with limited stage small cell lung carcinoma.预防性颅照射在局限期小细胞肺癌患者中的应用。
Cancer. 2010 Dec 15;116(24):5694-9. doi: 10.1002/cncr.25341. Epub 2010 Aug 27.
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Small Cells, Big Problems.小细胞,大问题。
Int J Radiat Oncol Biol Phys. 2018 May 1;101(1):4-5. doi: 10.1016/j.ijrobp.2018.01.065.
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Should all patients with SCLC receive prophylactic cranial irradiation if they have responded to treatment? The time has come to improve on a former standard.如果所有小细胞肺癌患者对治疗有反应,他们都应该接受预防性颅脑照射吗?改进以往标准的时候到了。
Clin Adv Hematol Oncol. 2015 Nov;13(11):729, 732-3.
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Should all patients with SCLC receive prophylactic cranial irradiation if they have responded to treatment? PCI should be offered in nearly all cases.如果所有小细胞肺癌患者对治疗有反应,他们都应该接受预防性颅脑照射吗?几乎在所有情况下都应该进行预防性颅脑照射。
Clin Adv Hematol Oncol. 2015 Nov;13(11):729-31.
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Is prophylactic cranial irradiation indicated for patients with extensive-stage small cell lung cancer with a complete response to first-line treatment?广泛期小细胞肺癌患者一线治疗达到完全缓解后,是否需要预防性颅脑照射?
Radiother Oncol. 2018 Jun;127(3):339-343. doi: 10.1016/j.radonc.2018.03.034. Epub 2018 May 7.

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Association of PTEN Gene SNPs rs2299939 With PFS in Patients With Small Cell Lung Cancer Treated With Early Radiotherapy.PTEN基因单核苷酸多态性rs2299939与接受早期放疗的小细胞肺癌患者无进展生存期的相关性
Front Genet. 2020 Apr 23;11:298. doi: 10.3389/fgene.2020.00298. eCollection 2020.