右美托咪定用于肌间沟阻滞术后镇痛的比较研究。
Postoperative analgesia with dexmedetomidine in interscalene block. Comparative study.
作者信息
Velázquez-Delgado E, Gaspar-Carrillo S P, Peña-Riveron A A, Mejía-Terrazas G E
机构信息
Sección de Anestesiología, Hospital Militar de Especialidades de la Mujer y Neonatología.
División de Anestesiología, Instituto Nacional de Rehabilitación.
出版信息
Rev Esp Anestesiol Reanim. 2017 Mar;64(3):137-143. doi: 10.1016/j.redar.2016.07.005. Epub 2016 Sep 9.
INTRODUCTION
Dexmedetomidine prolongs sensory block of ropivacaine. Our objective was to study whether this extension would produce better postoperative pain control compared to that produced by clonidine in patients undergoing arthroscopic shoulder.
MATERIALS AND METHODS
Study comparative, longitudinal, controlled, randomized into 3 groups. Control group I: ropivacaine 0.75% clonidine group II: 0.75% ropivacaine plus clonidine 1mg/kg group iiidexmedetomidine: 0.75% ropivacaine more dexmedetomidine 1mg/kg. Interscalene block single dose ultrasound-guided. Sensory and motor blockade, pain intensity, sedation level, heart rate, respiratory rate, blood pressure at 6, 12 and 24hours was measured.
RESULTS
Pain intensity at 6hours in groups I and II moderate to severe pain, mild pain group iii. At 12hours the groups IIand II showed moderate to severe pain by more than 60% of patients, and in group iiionly 10%. At 24hours I and II group 20% of patients they continued to moderate pain.
CONCLUSION
The prolonged interscalene block produced by dexmedetomidine provided better postoperative pain control during the first 24hours.
引言
右美托咪定可延长罗哌卡因的感觉阻滞时间。我们的目的是研究在接受肩关节镜手术的患者中，与可乐定相比，这种延长是否能产生更好的术后疼痛控制效果。
材料与方法
本研究为比较性、纵向、对照、随机分为3组。对照组I：0.75%罗哌卡因；可乐定组II：0.75%罗哌卡因加1mg/kg可乐定；右美托咪定组III：0.75%罗哌卡因加1mg/kg右美托咪定。采用单剂量超声引导下肌间沟阻滞。测量6、12和24小时时的感觉和运动阻滞、疼痛强度、镇静水平、心率、呼吸频率、血压。
结果
I组和II组6小时时疼痛强度为中度至重度疼痛，III组为轻度疼痛。12小时时，II组和III组超过60%的患者出现中度至重度疼痛，而III组仅为10%。24小时时，I组和II组20%的患者仍有中度疼痛。
结论
右美托咪定产生的延长肌间沟阻滞在术后24小时内提供了更好的疼痛控制。
Zotero 插件