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[运用血栓弹力图指导创伤后止血治疗:更多凝血因子浓缩剂及更少异体输血?]

[Use of thrombelastography to guide posttraumatic hemostatic therapy: More coagulation factor concentrates and less allogenic blood transfusion?].

作者信息

David J S, Imhoff E, Parat S, Augey L, Geay-Baillat M-O, Incagnoli P, Tazarourte K

机构信息

Service d'anesthésie réanimation, hospices civils de Lyon, centre hospitalier Lyon Sud, chemin du Grande-Revoyet, 69495 Pierre-Bénite cedex, France; Faculté de médecine Lyon Sud, université Claude-Bernard - Lyon 1, 69921 Oullins, France.

Service d'anesthésie réanimation, hospices civils de Lyon, centre hospitalier Lyon Sud, chemin du Grande-Revoyet, 69495 Pierre-Bénite cedex, France; Faculté de médecine Lyon Sud, université Claude-Bernard - Lyon 1, 69921 Oullins, France.

出版信息

Transfus Clin Biol. 2016 Nov;23(4):205-211. doi: 10.1016/j.tracli.2016.07.002. Epub 2016 Sep 5.

Abstract

Viscoelastic technics are used for 10 years and include the ROTEM and the TEG. These devices that exploit the viscoelastic properties of the clotting blood, allow a rapid and global analysis of the haemostatic process taking into account all the process interfering with haemostasis such as inflammation. It has been shown that the use of these technics in clinical situations such as trauma, postpartum haemorrhage, gastrointestinal bleeding or cardiac surgery may reduce the need for blood product, the cost and perhaps may improve the outcome of the patients. Thanks to a rapid identification of the underlying coagulation deficit, these technics facilitate decision-making during acute care and help to guide the treatment, particularly with coagulation factor's concentrate.

摘要

粘弹性技术已使用了10年,包括旋转血栓弹力图(ROTEM)和血栓弹力图(TEG)。这些利用凝血血液粘弹性特性的设备,能够对止血过程进行快速全面的分析,同时考虑到所有干扰止血的过程,如炎症。研究表明,在创伤、产后出血、胃肠道出血或心脏手术等临床情况下使用这些技术,可能会减少血液制品的需求、降低成本,甚至可能改善患者的治疗结果。由于能够快速识别潜在的凝血缺陷,这些技术有助于在急性护理期间做出决策,并指导治疗,特别是在使用凝血因子浓缩物时。

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