Rilke F, Pilotti S, Clemente C
Acta Cytol. 1978 Mar-Apr;22(2):71-9.
An attempt was made to diagnose cytologically non-Hodgkin's malignant lymphomas (ML) of the stomach on gastric smears in terms of the Kiel classification. This classification represents a more advanced approach for the identification of ML with regard to the cell type specificity, with some functional connotations as compared with previous classifications. The endoscopic brushing cell film studies, when compared with histology of endoscopic biopsies and/or surgical specimens, indicated a high accuracy of cell type identification. Sampling may represent problems in relation to the type of gross lesion. Specific cell types could be recognized in 20 of 25 cases of gastric involvement of ML. Six of nine cases of lymphoplasmacytoid ML revealed diagnostic cells, such as lymphoplasmacytoid cells, plasma cells, lymphocytes, and occasional immunoblasts. Six of seven cases of centrocytic ML had a large number of small cells with indented nuclei, and seven of eight centroblastic-centrocytic ML yielded a mixture of large centroblasts and small centrocytes. In addition to these 24 low-grade ML, one case of unclassifiable high-grade ML was diagnosed. Differential diagnostic problems within ML subtypes and with benign lesions, such as pseudolymphoma of the stomach, as well as malignant tumors and especially diffuse type gastric carcinoma, are taken into consideration.
尝试根据基尔分类法，通过胃涂片对胃的细胞学非霍奇金恶性淋巴瘤（ML）进行诊断。与先前的分类相比，该分类法在细胞类型特异性方面代表了一种更先进的ML识别方法，具有一些功能内涵。与内镜活检组织学和/或手术标本相比，内镜刷检细胞涂片研究显示细胞类型识别的准确率很高。取样可能因大体病变类型而存在问题。在25例胃受累的ML病例中，有20例可识别出特定的细胞类型。9例淋巴浆细胞样ML中有6例显示出诊断性细胞，如淋巴浆细胞样细胞、浆细胞、淋巴细胞和偶尔的免疫母细胞。7例中心细胞性ML中有6例有大量核凹陷的小细胞，8例中心母细胞-中心细胞性ML中有7例产生了大中心母细胞和小中心细胞的混合物。除了这24例低级别ML外，还诊断出1例无法分类的高级别ML。考虑到ML亚型内以及与良性病变（如胃假淋巴瘤）以及恶性肿瘤尤其是弥漫型胃癌的鉴别诊断问题。
