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计算美国全关节置换术中合并症的成本和风险。

Calculating the Cost and Risk of Comorbidities in Total Joint Arthroplasty in the United States.

作者信息

Hustedt Joshua W, Goltzer Oren, Bohl Daniel D, Fraser James F, Lara Nina J, Spangehl Mark J

机构信息

Department of Orthopedics, University of Arizona College of Medicine-Phoenix, Phoenix, Arizona.

Department of Orthopedics, Rush University Medical Center, Chicago, Illinois.

出版信息

J Arthroplasty. 2017 Feb;32(2):355-361.e1. doi: 10.1016/j.arth.2016.07.025. Epub 2016 Aug 9.

DOI:10.1016/j.arth.2016.07.025
PMID:27623745
Abstract

BACKGROUND

With increased scrutiny regarding the cost and safety of health care delivery, there is increasing interest in judicious patient selection for total joint arthroplasty (TJA) procedures. It is unknown which comorbidities incur the greatest increase in risk to the patient and cost to the system after TJA. Therefore, this study sought to characterize the association of common preoperative comorbidities with both the risk for postoperative in-hospital complications and the total hospital cost in patients undergoing TJA.

METHODS

A retrospective cohort study was conducted using the National Inpatient Sample. All elective, unilateral, primary or revision total knee or hip arthroplasty procedures in patients aged 40-95 years from 2008 to 2012 were identified. Common preoperative comorbidities were identified with use of clinical comorbidity software. Risk of complication and cost were calculated for each comorbidity.

RESULTS

A total of 4,323,045 patients were identified. Patient comorbidities increased the risk of major postoperative complications, with the highest risk associated with congestive heart failure (CHF; relative risk [RR], 4.402), valvular heart disease (VHD; RR, 3.209), and chronic obstructive pulmonary disease (COPD; RR, 2.813). Likewise, comorbidities increased overall hospital costs, with the largest additional costs associated with coagulopathy (+$3787), CHF (+$3701), and electrolyte disorders (+$3179). The cumulative number of comorbidities was associated with increased risk (R = 0.86) and cost (R = 0.90).

CONCLUSION

The findings of our study suggest that greater comorbidity burden is associated with increased risk and cost in TJA. Specifically, this article identifies the patient comorbidities that incur the greatest increase in postoperative complications (CHF, VHD, COPD) and cost (coagulopathy, CHF, electrolyte disorders) after TJA.

摘要

背景

随着对医疗保健服务成本和安全性的审查日益严格,对于全关节置换术(TJA)患者的明智选择越来越受到关注。目前尚不清楚哪些合并症会使患者在TJA后面临的风险增加最多,以及给医疗系统带来的成本增加最多。因此,本研究旨在描述常见术前合并症与TJA患者术后住院并发症风险及住院总费用之间的关联。

方法

使用国家住院样本进行一项回顾性队列研究。确定了2008年至2012年年龄在40 - 95岁的患者中所有择期、单侧、初次或翻修全膝关节或髋关节置换手术。使用临床合并症软件识别常见术前合并症。计算每种合并症的并发症风险和费用。

结果

共识别出4323045例患者。患者合并症增加了术后主要并发症的风险,其中与充血性心力衰竭(CHF;相对风险[RR],4.402)、心脏瓣膜病(VHD;RR,3.209)和慢性阻塞性肺疾病(COPD;RR,2.813)相关的风险最高。同样,合并症增加了总体住院费用,与凝血病(增加3787美元)、CHF(增加3701美元)和电解质紊乱(增加3179美元)相关的额外费用最高。合并症的累积数量与风险增加(R = 0.86)和费用增加(R = 0.90)相关。

结论

我们的研究结果表明,合并症负担越大,TJA的风险和费用越高。具体而言,本文确定了TJA后术后并发症(CHF、VHD、COPD)和费用(凝血病、CHF、电解质紊乱)增加最多的患者合并症。

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