NF-YC-RGL2 模块整合 GA 和 ABA 信号来调控拟南芥种子的萌发。
The NF-YC-RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis.
机构信息
Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China.
Guangdong Provincial Key Lab of Biotechnology for Plant Development, College of Life Sciences, South China Normal University, Guangzhou 510631, China.
出版信息
Nat Commun. 2016 Sep 14;7:12768. doi: 10.1038/ncomms12768.
The antagonistic crosstalk between gibberellic acid (GA) and abscisic acid (ABA) plays a pivotal role in the modulation of seed germination. However, the molecular mechanism of such phytohormone interaction remains largely elusive. Here we show that three Arabidopsis NUCLEAR FACTOR-Y C (NF-YC) homologues NF-YC3, NF-YC4 and NF-YC9 redundantly modulate GA- and ABA-mediated seed germination. These NF-YCs interact with the DELLA protein RGL2, a key repressor of GA signalling. The NF-YC-RGL2 module targets ABI5, a gene encoding a core component of ABA signalling, via specific CCAAT elements and collectively regulates a set of GA- and ABA-responsive genes, thus controlling germination. These results suggest that the NF-YC-RGL2-ABI5 module integrates GA and ABA signalling pathways during seed germination.
赤霉素 (GA) 和脱落酸 (ABA) 之间的拮抗串扰在调节种子萌发中起着关键作用。然而，这种植物激素相互作用的分子机制在很大程度上仍难以捉摸。在这里，我们表明拟南芥三个 NF-YC（NF-YC3、NF-YC4 和 NF-YC9）同源物冗余地调节 GA 和 ABA 介导的种子萌发。这些 NF-YC 与 DELLA 蛋白 RGL2 相互作用，RGL2 是 GA 信号的关键抑制子。NF-YC-RGL2 模块通过特定的 CCAAT 元件靶向 ABI5，ABI5 是编码 ABA 信号核心成分的基因，并共同调节一组 GA 和 ABA 响应基因，从而控制萌发。这些结果表明，NF-YC-RGL2-ABI5 模块在种子萌发过程中整合了 GA 和 ABA 信号通路。
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