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成功从一名已故器官捐献者身上获取并移植包括面部、双侧上肢以及胸腹部器官在内的11个器官。

Successful Recovery and Transplantation of 11 Organs Including Face, Bilateral Upper Extremities, and Thoracic and Abdominal Organs From a Single Deceased Organ Donor.

作者信息

Tullius Stefan G, Pomahac Bohdan, Kim Heung Bae, Carty Matthew J, Talbot Simon G, Nelson Helen M, Delmonico Francis L

机构信息

1 Division of Transplant Surgery, Brigham and Women's Hospital, Boston, MA. 2 Division of Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, MA. 3 Pediatric Transplant Center, Children's Hospital, Boston, MA. 4 New England Organ Bank, Waltham, MA.

出版信息

Transplantation. 2016 Oct;100(10):2226-9. doi: 10.1097/TP.0000000000001200.

DOI:10.1097/TP.0000000000001200
PMID:27624820
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5030114/
Abstract

We report on the to date largest recovery of 11 organs from a single deceased donor with the transplantation of face, bilateral upper extremities, heart, 1 lung, liver (split for 2 recipients), kidneys, pancreas, and intestine. Although logistically challenging, this case demonstrates the feasibility and safety of the recovery of multiple thoracic and abdominal organs with multiple vascular composite allotransplants and tissues. Our experience of 8 additional successful multiple vascular composite allotransplants, thoracic, and abdominal organ recoveries suggests that such procedures are readily accomplishable from the same deceased donor.

摘要

我们报告了迄今为止从一名已故供体身上成功获取11个器官并进行移植的案例,包括面部、双侧上肢、心脏、1个肺、肝脏(分为2个受者)、肾脏、胰腺和小肠。尽管在后勤保障方面具有挑战性,但该案例证明了同时进行多个胸部和腹部器官以及多种血管化复合组织异体移植的可行性和安全性。我们另外8例成功的血管化复合组织异体移植、胸部和腹部器官获取经验表明,从同一已故供体进行此类手术是完全可行的。

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Avascular necrosis of the humeral head following bilateral upper extremity vascular composite allotransplantation: a case report.双侧上肢血管化复合组织异体移植术后肱骨头缺血性坏死:一例报告
Case Reports Plast Surg Hand Surg. 2017 Jul 6;4(1):60-64. doi: 10.1080/23320885.2017.1345635. eCollection 2017.

本文引用的文献

1
Algorithm for total face and multiorgan procurement from a brain-dead donor.从脑死亡供体获取全脸面和多器官的算法。
Am J Transplant. 2013 Oct;13(10):2743-9. doi: 10.1111/ajt.12382. Epub 2013 Aug 5.
2
The International Registry on Hand and Composite Tissue allotransplantation.国际手部及复合组织异体移植登记处。
Clin Transpl. 2011:247-53.
3
Logistics and strategy of multiorgan procurement involving total face allograft.涉及全颜面同种异体移植的多器官获取的物流和策略。
Am J Transplant. 2011 May;11(5):1091-7. doi: 10.1111/j.1600-6143.2011.03489.x. Epub 2011 Mar 28.