[大鼠鞘内空间的显微外科导管插入术用于药物的慢性输注]
[Microsurgical catheterization of the intrathecal space in the rat for chronic infusion of drugs].
作者信息
González-Darder J M, Gómez-Cárdenas E, Gil-Salú J L
出版信息
Rev Esp Anestesiol Reanim. 1989 May-Jun;36(3):153-6.
PMID:2762610
Abstract
An original technique for placement of intrathecal catheters suitable for drug administration is described. For implantation a microsurgical laminectomy is carried out, opening the dura mater and placing the catheter under surgical microscope control. Only a few instrumentation is mandatory. The mean time for this surgery was between 15 and 20 minutes. A 10% of the animals operated on developed neurological deficits and must be dropped. The mortality rate was a 5%. No catheter malfunctions were found.
摘要
本文描述了一种用于放置适合药物给药的鞘内导管的原创技术。植入时需进行显微外科椎板切除术，打开硬脑膜并在手术显微镜控制下放置导管。仅需少数器械。该手术的平均时间为15至20分钟。接受手术的动物中有10%出现神经功能缺损，必须淘汰。死亡率为5%。未发现导管故障。
相似文献
1
[Microsurgical catheterization of the intrathecal space in the rat for chronic infusion of drugs].[大鼠鞘内空间的显微外科导管插入术用于药物的慢性输注]
Rev Esp Anestesiol Reanim. 1989 May-Jun;36(3):153-6.
2
Lumbar catheterization of the subarachnoid space with a 32-gauge polyurethane catheter in the rat.在大鼠中使用32号聚氨酯导管进行蛛网膜下腔腰椎置管。
Eur J Pain. 2000;4(1):111-3. doi: 10.1053/eujp.1999.0157.
3
Subdural intrathecal catheter placement: experience with two cases.硬膜下鞘内导管置入术：两例经验
Pain Physician. 2008 Sep-Oct;11(5):677-80.
4
Simple catheter preparation for permitting bolus intrathecal administration during chronic intrathecal infusion.用于在慢性鞘内输注期间允许推注鞘内给药的简易导管准备方法。
Pharmacol Biochem Behav. 1986 Aug;25(2):483-5. doi: 10.1016/0091-3057(86)90028-6.
5
Chronic lumbar intrathecal catheterization in the rat with reduced-length spinal compression.大鼠慢性腰段鞘内导管插入术伴脊髓缩短性压迫
Physiol Behav. 1984 Jul;33(1):159-61. doi: 10.1016/0031-9384(84)90026-x.
6
A modified procedure for lumbar intrathecal catheterization in rats.一种改良的大鼠腰段鞘内导管插入术
Neurol Res. 2016 Aug;38(8):725-32. doi: 10.1080/01616412.2016.1196870. Epub 2016 Jun 16.
7
Distribution of intrathecal catheter positions in rat.大鼠鞘内导管位置的分布
Acta Anaesthesiol Scand. 2001 May;45(5):608-11. doi: 10.1034/j.1399-6576.2001.045005608.x.
8
An improved method for protecting and fixing the lumbar catheters placed in the spinal subarachnoid space of rats.一种用于保护和固定置于大鼠脊髓蛛网膜下腔的腰段导管的改进方法。
J Neurosci Methods. 2009 Oct 15;183(2):114-8. doi: 10.1016/j.jneumeth.2009.06.020. Epub 2009 Jun 24.
9
[A model for microsurgical interference of the rat cranium].[大鼠颅骨显微外科干预模型]
Z Exp Chir Transplant Kunstliche Organe. 1988;21(6):334-9.
10
Loop dialysis catheter: a technology for chronic spinal dialysis in a freely moving rat.环形透析导管：一种用于自由活动大鼠慢性脊髓透析的技术。
Methods Mol Med. 2004;99:99-108. doi: 10.1385/1-59259-770-X:099.
引用本文的文献
1
[Comparison of different methods for drug delivery via the lumbar spinal subarachnoid space in rats].[大鼠经腰椎蛛网膜下腔给药不同方法的比较]
Nan Fang Yi Ke Da Xue Xue Bao. 2019 Oct 30;39(10):1246-1252. doi: 10.12122/j.issn.1673-4254.2019.10.18.
Zotero 插件