Lee Kye-Sung, Hur Hwan, Sung Ha-Young, Kim I Jong, Kim Geon-Hee
Opt Lett. 2016 Sep 15;41(18):4241-4. doi: 10.1364/OL.41.004241.
We demonstrate a fiber-optic-based parallel optical coherence tomography (OCT) using spectrally encoded extended illumination with a common-path handheld probe, where the flexibility and robustness of the system are significantly improved, which is critical in the clinical environment. To the best of our knowledge, we present the first parallel OCT based on fiber optics including a fiber coupler with a sensitivity of 94 dB, which is comparable to that of point-scanning OCT. We also investigated the effect of the phase stability of the fiber-based interferometry on the parallel OCT system by comparing the common-path OCT with two-arm OCT. Using the homemade common-path handheld probe based on a Mirau interferometer, the phase stability was 32 times better than that of the two-arm OCT. The axial resolution of the common-path OCT was measured as 5.1±0.3 μm. To demonstrate the in vivo imaging performance of the fiber-optic-based parallel OCT, human skin was imaged.
我们展示了一种基于光纤的并行光学相干断层扫描(OCT)技术,该技术使用具有共光路手持探头的光谱编码扩展照明,显著提高了系统的灵活性和稳健性,这在临床环境中至关重要。据我们所知,我们提出了首个基于光纤的并行OCT,其包括一个灵敏度为94 dB的光纤耦合器,与点扫描OCT的灵敏度相当。我们还通过将共光路OCT与双臂OCT进行比较,研究了基于光纤的干涉测量的相位稳定性对并行OCT系统的影响。使用基于Mirau干涉仪自制的共光路手持探头,其相位稳定性比双臂OCT好32倍。共光路OCT的轴向分辨率测量为5.1±0.3μm。为了展示基于光纤的并行OCT的体内成像性能,对人体皮肤进行了成像。