Nayak Madhurima K, Singh Neha
Senior Resident, Department of Ophthalmology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
Resident, Department of Ophthalmology, Kasturba Medical College, Manipal University , Mangalore, Karnataka, India .
J Clin Diagn Res. 2016 Jul;10(7):ND03-4. doi: 10.7860/JCDR/2016/18699.8164. Epub 2016 Jul 1.
Multiple myeloma cripples the human body in many ways, one of them being decreased immunity. Infections occurring spontaneously can increase the morbidity. We report a case of an elderly lady with multiple myeloma on treatment and uncontrolled diabetes, who developed loss of vision, swelling and redness of left eye of 4 days duration. There was no history of injury or entry of a foreign body. She also had left arm cellulitis. Ocular examination revealed visual acuity of 6/36 in right eye and no perception of light in left eye. Anterior segment of the right eye was insignificant while the left eye showed features suggestive of panophthalmitis. B scan revealed choroidal detachment and confirmed panophthalmitis. She underwent evisceration of the left eye. The cause of spontaneous infections is an immunocompromised state due to multiple myeloma and uncontrolled diabetes. This case report highlights the propensity of multiple myeloma to cause infections of the eye debilitating enough to cause severe visual morbidity.
多发性骨髓瘤会在许多方面损害人体,其中之一就是免疫力下降。自发发生的感染会增加发病率。我们报告一例老年女性患者,患有多发性骨髓瘤且糖尿病控制不佳,正在接受治疗,出现了持续4天的视力丧失、左眼肿胀和发红。没有受伤或异物进入史。她还患有左臂蜂窝织炎。眼部检查显示右眼视力为6/36,左眼无光感。右眼前段无明显异常,而左眼表现出提示全眼球炎的特征。B超显示脉络膜脱离并确诊为全眼球炎。她接受了左眼眼球摘除术。自发感染的原因是多发性骨髓瘤和糖尿病控制不佳导致的免疫功能低下状态。本病例报告强调了多发性骨髓瘤导致眼部感染的倾向,这种感染足以使人衰弱并导致严重的视觉发病率。