Jing Bowen, Tang Shanshan, Wu Liang, Wang Supin, Wan Mingxi
Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Key Laboratory of Biomedical Information Engineering of Ministry of Education, Department of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
Ultrasound Med Biol. 2016 Dec;42(12):2812-2825. doi: 10.1016/j.ultrasmedbio.2016.07.023. Epub 2016 Sep 12.
Ultrafast plane wave ultrasonography is employed in this study to visualize the vibration of the larynx and quantify the vibration phase as well as the vibration amplitude of the laryngeal tissue. Ultrasonic images were obtained at 5000 to 10,000 frames/s in the coronal plane at the level of the glottis. Although the image quality degraded when the imaging mode was switched from conventional ultrasonography to ultrafast plane wave ultrasonography, certain anatomic structures such as the vocal folds, as well as the sub- and supraglottic structures, including the false vocal folds, can be identified in the ultrafast plane wave ultrasonic image. The periodic vibration of the vocal fold edge could be visualized in the recorded image sequence during phonation. Furthermore, a motion estimation method was used to quantify the displacement of laryngeal tissue from hundreds of frames of ultrasonic data acquired. Vibratory displacement waveforms of the sub- and supraglottic structures were successfully obtained at a high level of ultrasonic signal correlation. Moreover, statistically significant differences in vibration pattern between the sub- and supraglottic structures were found. Variation of vibration amplitude along the subglottic mucosal surface is significantly smaller than that along the supraglottic mucosal surface. Phase delay of vibration along the subglottic mucosal surface is significantly smaller than that along the supraglottic mucosal surface.
本研究采用超快平面波超声成像技术来可视化喉部振动，并量化喉部组织的振动相位和振动幅度。在声门水平的冠状面以5000至10000帧/秒的速度获取超声图像。尽管当成像模式从传统超声检查切换到超快平面波超声检查时图像质量下降，但在超快平面波超声图像中仍可识别某些解剖结构，如声带以及声门下和声门上结构，包括假声带。在发声过程中，声带边缘的周期性振动可在记录的图像序列中可视化。此外，使用运动估计方法从采集的数百帧超声数据中量化喉部组织的位移。在高超声信号相关性水平下成功获得了声门下和声门上结构的振动位移波形。此外，还发现声门下和声门上结构之间的振动模式存在统计学上的显著差异。沿声门下黏膜表面的振动幅度变化明显小于沿声门上黏膜表面的变化。沿声门下黏膜表面的振动相位延迟明显小于沿声门上黏膜表面的延迟。
