RYP1基因作为组织胞浆菌病分子诊断的靶点。
RYP1 gene as a target for molecular diagnosis of histoplasmosis.
作者信息
Brilhante Raimunda Sâmia Nogueira, Guedes Glaucia Morgana de Melo, Riello Giovanna Barbosa, Ribeiro Joyce Fonteles, Alencar Lucas Pereira, Bandeira Silviane Praciano, Castelo-Branco Débora Souza Collares Maia, Oliveira Jonathas Sales, Freire Janaína Maria Maia, Mesquita Jacó Ricarte Lima de, Camargo Zoilo Pires de, Cordeiro Rossana de Aguiar, Rocha Marcos Fábio Gadelha, Sidrim José Júlio Costa
机构信息
Specialized Medical Mycology Center, Postgraduate Program in Medical Microbiology, Department of Pathology and Legal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Specialized Medical Mycology Center, Postgraduate Program in Medical Microbiology, Department of Pathology and Legal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
出版信息
J Microbiol Methods. 2016 Nov;130:112-114. doi: 10.1016/j.mimet.2016.09.006. Epub 2016 Sep 13.
This study analyzed the RYP1 gene as a target for the molecular diagnosis of histoplasmosis. This assay detected fungal DNA in 13/13 blood samples from HIV/AIDS-patients with histoplasmosis. Therefore, the detection of RYP1 gene in whole blood sample is a quick and sensitive test to diagnose histoplasmosis.
本研究分析了RYP1基因作为组织胞浆菌病分子诊断的靶点。该检测方法在13例患有组织胞浆菌病的HIV/AIDS患者的13份血样中检测到了真菌DNA。因此，在全血样本中检测RYP1基因是诊断组织胞浆菌病的一种快速且灵敏的检测方法。
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