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选择性十二指肠溃疡手术中壁细胞迷走神经切断术和迷走神经干切断术——6至12年后的结果

Parietal cell vagotomy and truncal vagotomy in elective duodenal ulcer surgery--results after six to twelve years.

作者信息

Elfberg B A, Nilsson F, Selking O

机构信息

Department of Surgery, University Hospital, Uppsala, Sweden.

出版信息

Ups J Med Sci. 1989;94(2):129-36. doi: 10.3109/03009738909178558.

Abstract

In a randomized trial between 1974 and 1980, parietal cell vagotomy (PCV) was compared with truncal vagotomy (TV) in the treatment of duodenal ulcer in 106 patients. After a mean period of 3.9 years no significant differences were found between PCV and TV patients with respect to Visick grading and recurrence rates. Nor did the preoperative location of the ulcer-prepyloric or duodenal-significantly influence the recurrences. The latter follow-up reported in 1981, showed that PCV was not superior to TV. The present paper describes a re-analysis of the same material in 1985. After a mean observation time of 8.7 years no significant differences in the ulcer recurrence rate were found between PCV and TV. Equal patient satisfaction with the two procedures was found. In patients with prepyloric ulcers, preoperatively, there was a higher recurrence rate among those who had undergone PCV than TV.

摘要

在1974年至1980年的一项随机试验中,对106例十二指肠溃疡患者比较了壁细胞迷走神经切断术(PCV)与迷走神经干切断术(TV)的治疗效果。平均3.9年后,在Visick分级和复发率方面,PCV组和TV组患者之间未发现显著差异。溃疡的术前位置(幽门前或十二指肠)也未对复发产生显著影响。1981年报道的后续研究表明,PCV并不优于TV。本文描述了1985年对相同资料的重新分析。平均观察8.7年后,PCV组和TV组在溃疡复发率方面未发现显著差异。两种手术方式的患者满意度相当。术前有幽门前溃疡的患者中,接受PCV手术的患者复发率高于接受TV手术的患者。

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