Hamamoto Y, Harada S, Kobayashi S, Yamaguchi K, Iijima H, Manabe S, Tsurumi T, Aizawa H, Yamamoto N
Department of Virology and Parasitology, Yamaguchi University School of Medicine, Japan.
Vox Sang. 1989;56(4):230-6. doi: 10.1111/j.1423-0410.1989.tb02034.x.
We propose a new method to rid solutions of a virus by using a novel regenerated multilayered structured cellulose membrane (BMM). When the filtrate of human immunodeficiency virus (HIV) preparation was obtained through BMM it showed no infectivity. Electron microscopic observation revealed that HIV was completely caught by the multilayers of the BMM. Conveniently, BMM was seldomly found to adsorb protein molecules and also to have a high filtration rate. These characteristics may have a use in the removal of other variously sized pathogenic agents from plasma.
我们提出了一种通过使用新型再生多层结构纤维素膜（BMM）来去除溶液中病毒的新方法。当通过BMM获得人类免疫缺陷病毒（HIV）制剂的滤液时，其显示无感染性。电子显微镜观察显示HIV被BMM的多层结构完全捕获。方便的是，很少发现BMM吸附蛋白质分子，并且其还具有高过滤速率。这些特性可能可用于从血浆中去除其他各种大小的病原体。
