Zakzanis Konstantine K, Grimes Kyrsten M
a Department of Psychology , University of Toronto Scarborough , Toronto , Ontario , Canada.
Appl Neuropsychol Adult. 2017 Nov-Dec;24(6):559-565. doi: 10.1080/23279095.2016.1225216. Epub 2016 Sep 16.
It is well established that most people recover soon after a mild traumatic brain injury (mTBI), yet protracted neuropsychological impairment is evident in many individuals. We sought to elucidate the relationship between apathy and neuropsychological impairment and disability as it pertains to real-world function in patients who sustained a mTBI reporting and demonstrating protracted neuropsychological impaired (i.e., more than three months post-injury). We employed a battery of neuropsychological and psychological measures, along with a measure of apathy in 104 patients who sustained a mTBI reporting neuropsychological complaints (38 in the not disabled group and 66 in the disabled group). Their ability to return to work was used as proxy for real-world disability. Specific deficits in verbal fluency, memory, and information processing predicted real-world disability but apathy did not, suggesting that psychological factors may play less of a mediating role than specific neuropsychological factors in the relationship between impairment and real world disability. Our research furthers our understanding of the cognitive and psychological differences that exist in patients with mTBI who have real-world disability compared to those who do not.
众所周知，大多数人在轻度创伤性脑损伤（mTBI）后很快就能康复，但许多人会出现长期的神经心理障碍。我们试图阐明冷漠与神经心理障碍及残疾之间的关系，因为这与报告并表现出长期神经心理障碍（即受伤后三个月以上）的mTBI患者的现实世界功能有关。我们对104名报告有神经心理问题的mTBI患者进行了一系列神经心理和心理测试，以及一项冷漠测试（非残疾组38人，残疾组66人）。他们重返工作的能力被用作现实世界残疾的指标。言语流畅性、记忆力和信息处理方面的特定缺陷可预测现实世界的残疾，但冷漠则不能，这表明在损伤与现实世界残疾的关系中，心理因素可能比特定的神经心理因素起到的中介作用更小。我们的研究进一步加深了我们对有现实世界残疾的mTBI患者与无此残疾的患者之间存在的认知和心理差异的理解。
