Böhm F, Wenzel M, Gerhardt H J
Department of Dermatology, Humboldt University, Berlin, GDR.
Acta Otolaryngol. 1989 Jul-Aug;108(1-2):136-41. doi: 10.3109/00016488909107405.
Proceeding from the cultivation of human epidermal cells we succeeded in cultivating mucosal cells from ethmoidal sinuses and in characterizing them by scanning electron microscopy. In particular, the reaction of ciliated cells and goblet cells in vitro and their ability to reproduce were compared with the reaction of keratinocytes. Ethmoidal sinus cells show adhesion and spreading rates similar to those of skin cells; they proliferate faster (3 days up to monolayer) and differentiate in vitro to ciliated epithelia. It would seem possible to use them for lining of plastic prostheses for the respiratory tract.
从人表皮细胞培养出发,我们成功培养了筛窦黏膜细胞,并通过扫描电子显微镜对其进行了表征。特别是,将体外纤毛细胞和杯状细胞的反应及其增殖能力与角质形成细胞的反应进行了比较。筛窦细胞的黏附率和铺展率与皮肤细胞相似;它们增殖更快(3天可达单层),并在体外分化为纤毛上皮。似乎可以将它们用于呼吸道塑料假体的内衬。