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[成人社区获得性肺炎的疫苗接种。预防领域专家的立场文件]

[Vaccination against community acquired pneumonia in adult patients. A position paper by Neumoexpertos en Prevención].

作者信息

Redondo E, Rivero I, Vargas D A, Mascarós E, Díaz-Maroto J L, Linares M, Valdepérez J, Gil A, Molina J, Jimeno I, Ocaña D, Martinón-Torres F

机构信息

Médico de Familia, Coordinadora del Grupo de Actividades Preventivas y Salud Pública SEMERGEN, Centro de Salud Internacional Madrid Salud, Ayuntamiento de Madrid, Madrid, España.

Pediatra, Departamento de Pediatría Clínica, Infectológica y Traslacional, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España; Genética, Vacunas, Infecciones y Pediatría (GENVIP), Instituto de Investigación de Santiago, Santiago de Compostela, A Coruña, España.

出版信息

Semergen. 2016 Oct;42(7):464-475. doi: 10.1016/j.semerg.2016.07.009. Epub 2016 Sep 15.

Abstract

INTRODUCTION

Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality in adults. The annual incidence of CAP in adults in Spain ranges from 3 to 14 cases per 1,000 inhabitants. Current clinical guidelines primarily focus on the therapeutic approach to CAP rather than its prevention. The aim of this study is to develop and propose a practical guide for CAP prevention through vaccination in Spain according to available vaccines and evidence.

METHODS

A literature review and expert opinion.

RESULTS

Pneumococcal and influenza vaccines are the main preventive tools available against CAP. Age, chronic diseases, and immunosuppression are risk factors for pneumonia, so these populations should be a priority for vaccination. In addition, influenza and pneumococcal vaccination is considered advisable in healthy adults under 60 years of age, and anyone with risk condition for CAP, irrespective of age. The influenza vaccine will be administered seasonally, while pneumococcal vaccination can be administered at any time of the year.

CONCLUSIONS

Vaccination against pneumococcus and influenza in adults can help to reduce the burden of CAP and its associated complications. The available evidence supports the priority indications set out in this guide, and it would be advisable to try to achieve a wide circulation and practical implementation of these recommendations.

摘要

引言

社区获得性肺炎(CAP)是成人发病和死亡的主要原因。西班牙成人CAP的年发病率为每1000名居民3至14例。目前的临床指南主要关注CAP的治疗方法而非预防。本研究的目的是根据现有疫苗和证据,制定并提出一份在西班牙通过接种疫苗预防CAP的实用指南。

方法

文献综述和专家意见。

结果

肺炎球菌疫苗和流感疫苗是预防CAP的主要可用工具。年龄、慢性病和免疫抑制是肺炎的危险因素,因此这些人群应作为疫苗接种的优先对象。此外,60岁以下的健康成年人以及任何有CAP风险状况的人,无论年龄大小,都建议接种流感疫苗和肺炎球菌疫苗。流感疫苗将按季节接种,而肺炎球菌疫苗可在一年中的任何时间接种。

结论

成人接种肺炎球菌疫苗和流感疫苗有助于减轻CAP及其相关并发症的负担。现有证据支持本指南中规定的优先指征,建议努力使这些建议得到广泛传播和实际实施。

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