Steen Willemijn, Blom Rachel, Busch Olivier, Gerhards Michael, Besselink Marc, Dijk Frederike, Festen Sebastiaan
Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands.
J Surg Oncol. 2016 Nov;114(6):743-751. doi: 10.1002/jso.24402. Epub 2016 Sep 19.
The poor survival of patients with resectable pancreatic cancer might be related to the presence of occult peritoneal tumor cells (OPTC). This systematic review studies the prognostic value of cytology and carcinoembryonic antigen (CEA) by real-time polymerase chain reaction in peritoneal fluid. The results suggest that presence of OPTC is related to a worse survival in patients with resectable pancreatic cancer. Future studies should investigate its possible role in selecting patients for specific treatment strategies. J. Surg. Oncol. 2016;114:743-751. © 2016 Wiley Periodicals, Inc.
可切除胰腺癌患者生存率低可能与隐匿性腹膜肿瘤细胞（OPTC）的存在有关。本系统评价研究了通过实时聚合酶链反应检测腹水细胞学及癌胚抗原（CEA）的预后价值。结果表明，OPTC的存在与可切除胰腺癌患者较差的生存率相关。未来研究应探讨其在选择特定治疗策略患者中的潜在作用。《外科肿瘤学杂志》2016年；114:743 - 751。©2016威利期刊公司
