Nannei Claudia, Goldin Shoshanna, Torelli Guido, Fatima Hiba, Kumar Kaveri, Bubb-Humfryes Oliver, Stenson Bo, Sparrow Erin
World Health Organization, Switzerland.
World Health Organization, Switzerland.
Vaccine. 2016 Oct 26;34(45):5393-5399. doi: 10.1016/j.vaccine.2016.08.040. Epub 2016 Sep 16.
Ten years after the launch of the Global Action Plan for Influenza Vaccines (GAP), the World Health Organization (WHO) surveyed stakeholders to understand their perceptions of what the programme had achieved. This article provides a summary of the findings; the full report will be available on-line on the GAP website in November 2016 (http://www.who.int/influenza_vaccines_plan/en/). Seventy-seven responses were received from stakeholders including medical doctors, national influenza center officials, country immunization programme teams, surveillance and disease centers, policy-makers, researchers, vaccine manufacturers, and non-governmental organizations from 28 countries, representing all six WHO regions. Respondents cited GAP's biggest successes as capacity building in developing countries; raising international awareness of global needs in the event of a pandemic; and collaborative alignment of influenza stakeholders. The most commonly reported challenges were the limited progress in development of a broadly protective or universal vaccine and the perceived absence of a major increase in seasonal demand. These findings aligned with the perception that less global progress had been made under the third GAP objective, focused on research and development of better vaccines, than on increasing seasonal vaccine use (objective 1) and pandemic vaccine production capacity (objective 2). Respondents explained what they saw as the major challenges to development of better vaccines, including to development of a universal influenza vaccine. The majority of respondents agreed that the goal chosen at the GAP II consultation is still relevant. Results highlighted the importance of promoting research and development of better vaccines, both for facilitating uptake of seasonal vaccines and for ensuring timely vaccine availability in the event of a pandemic. As the GAP concludes its mandate this year, these findings will contribute to discussions on the impact of programme closure and how to address the key issues facing influenza stakeholders thereafter.
《全球流感疫苗行动计划》(GAP)发布十年后,世界卫生组织(WHO)对利益相关者进行了调查,以了解他们对该计划所取得成就的看法。本文提供了调查结果的摘要;完整报告将于2016年11月在GAP网站(http://www.who.int/influenza_vaccines_plan/en/)上在线发布。共收到来自28个国家的77份利益相关者的回复,包括医生、国家流感中心官员、国家免疫规划团队、监测和疾病中心、政策制定者、研究人员、疫苗制造商以及非政府组织,代表了WHO的所有六个区域。受访者认为GAP的最大成功在于发展中国家的能力建设;提高国际社会对大流行期间全球需求的认识;以及流感利益相关者的协同合作。最常报告的挑战是在研发具有广泛保护作用的通用疫苗方面进展有限,以及季节性需求未见大幅增长。这些调查结果与以下看法一致,即与增加季节性疫苗使用(目标1)和大流行疫苗生产能力(目标2)相比,在以研发更好的疫苗为重点的第三个GAP目标下,全球取得的进展较少。受访者解释了他们认为在研发更好的疫苗(包括通用流感疫苗)方面面临的主要挑战。大多数受访者同意,在GAP II磋商中选定的目标仍然具有相关性。结果凸显了促进研发更好疫苗的重要性,这既有助于推动季节性疫苗的使用,也有助于在大流行时确保及时提供疫苗。由于GAP今年将结束其任务,这些调查结果将有助于讨论该计划结束的影响以及此后如何应对流感利益相关者面临的关键问题。