Bétrémieux P, Casadevall I, Odent S, Jouan H, Lefrançois C, Naber M C, Morellec J, Le Marec B
Service de Pédiatrie-Génétique médicale, CHU de Rennes.
Arch Fr Pediatr. 1989 May;46(5):341-5.
Among 125 neonatal deaths which occurred between 1985 and 1987 in a neonatal intensive care unit, 90 autopsies (72%) were performed. Autopsies in 58 cases (64%) confirmed antemortem conclusions. In 26 cases (28%) post-mortem examination rectified antemortem findings whereas in 6 cases (6.6%) it did not contribute to a better understanding of the cause of death. When there was a risk of an heritable disease and genetic counselling was necessary (31 cases), the autopsy permitted to provide the diagnosis in 4 cases and to reassure the family in 17. In 23 cases the post-mortem examination had to be completed by perimortem studies to be contributive. As no antemortem data allowed to predict the value of the autopsy, a postmortem study should by systematically requested in cases of death during the neonatal period.
在1985年至1987年间，某新生儿重症监护病房发生的125例新生儿死亡病例中，进行了90例尸检（72%）。58例（64%）尸检证实了生前诊断结论。26例（28%）尸检纠正了生前检查结果，而6例（6.6%）尸检对更好地理解死亡原因并无帮助。当存在遗传性疾病风险且需要进行遗传咨询时（31例），尸检确诊了4例，并让17例患儿家庭安心。23例尸检必须通过濒死期研究来完善，才能提供有用信息。由于生前资料无法预测尸检的价值，因此对于新生儿期死亡病例，应系统性地要求进行尸检研究。
