Bank H L, Wise C, Hargrove K, Spicer S S
Exp Hematol. 1978 Jun;6(6):528-38.
The density and size distribution of intramembranous particles (IMP) were determined for cells of the erythroid series. The number and size of IMP were measured on both fracture faces of erythroblastic leukemia cells, phenylhydrazine-induced reticulocytes and mature erythrocytes. We found that the number of IMP adhering to the protoplasmic fracture face of the plasma membrane increased with increasing maturation, while the number of particles adhering to the external fracture face did not correlate with maturational stage. In general, the mean size of particles adhering to both fracture faces decreased with increasing maturation after the erythroblastic stage. We interpret these results to mean that the IMP seen are derived from more than one macromolecular species and that they are distributed asymmetrically in the plasma membrane.
测定了红系细胞的膜内颗粒（IMP）的密度和大小分布。在成红细胞白血病细胞、苯肼诱导的网织红细胞和成熟红细胞的两个断裂面上测量了IMP的数量和大小。我们发现，附着在质膜原生质断裂面上的IMP数量随着成熟度的增加而增加，而附着在外表面断裂面上的颗粒数量与成熟阶段无关。一般来说，在成红细胞阶段之后，附着在两个断裂面上的颗粒平均大小随着成熟度的增加而减小。我们将这些结果解释为，所观察到的IMP来自不止一种大分子物质，并且它们在质膜中不对称分布。
