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支气管内瓣膜置入治疗持续性肺漏气

Management of Prolonged Pulmonary Air Leaks With Endobronchial Valve Placement.

作者信息

Bakhos Charles, Doelken Peter, Pupovac Stevan, Ata Ashar, Fabian Tom

机构信息

Section of Thoracic Surgery.

Division of Pulmonary Medicine.

出版信息

JSLS. 2016 Jul-Sep;20(3). doi: 10.4293/JSLS.2016.00055.

Abstract

BACKGROUND

Prolonged pulmonary air leaks (PALs) are associated with increased morbidity and extended hospital stay. We sought to investigate the role of bronchoscopic placement of 1-way valves in treating this condition.

METHODS

We queried a prospectively maintained database of patients with PAL lasting more than 7 days at a tertiary medical center. Main outcome measures included duration of chest tube placement and hospital stay before and after valve deployment.

RESULTS

Sixteen patients were eligible to be enrolled from September 2012 through December 2014. One patient refused to give consent, and in 4 patients, the source of air leak could not be identified with bronchoscopic balloon occlusion. Eleven patients (9 men; mean age, 65 ± 15 years) underwent bronchoscopic valve deployment. Eight patients had postoperative PAL and 3 had a secondary spontaneous pneumothorax. The mean duration of air leak before valve deployment was 16 ± 12 days, and the mean number of implanted valves was 1.9 (median, 2). Mean duration of hospital stay before and after valve deployment was 18 and 9 days, respectively (P = .03). Patients who had more than a 50% decrease in air leak on digital monitoring had the thoracostomy tube removed within 3-6 days. There were no procedural complications related to deployment or removal of the valves.

CONCLUSIONS

Bronchoscopic placement of 1-way valves is a safe procedure that could help manage patients with prolonged PAL. A prospective randomized trial with cost-efficiency analysis is necessary to better define the role of this bronchoscopic intervention and demonstrate its effect on air leak duration.

摘要

背景

长时间肺漏气(PALs)与发病率增加和住院时间延长相关。我们旨在研究支气管镜下置入单向阀在治疗这种情况中的作用。

方法

我们查询了一家三级医疗中心前瞻性维护的PAL持续超过7天的患者数据库。主要结局指标包括置管引流时间和置入瓣膜前后的住院时间。

结果

2012年9月至2014年12月期间,16例患者符合纳入标准。1例患者拒绝签署知情同意书,4例患者经支气管镜球囊封堵无法确定漏气来源。11例患者(9例男性;平均年龄65±15岁)接受了支气管镜瓣膜置入术。8例患者为术后PAL,3例为继发性自发性气胸。瓣膜置入前漏气的平均持续时间为16±12天,平均置入瓣膜数量为1.9个(中位数为2个)。瓣膜置入前后的平均住院时间分别为18天和9天(P = 0.03)。数字监测显示漏气减少超过50%的患者在3 - 6天内拔除了胸腔引流管。没有与瓣膜置入或拔除相关的操作并发症。

结论

支气管镜下置入单向阀是一种安全的操作,有助于管理长时间PAL患者。有必要进行一项具有成本效益分析的前瞻性随机试验,以更好地确定这种支气管镜干预的作用,并证明其对漏气持续时间的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f60/5019191/d99895687012/jls9991535800001.jpg

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