Hafeez Muhammad, Kadir Ehsan, Aijaz Anjum
Dr. Muhammad Hafeez, FCPS(Med), FCPS(Gastro) FACG, MASGE(USA), FRSPH, SCE RCP Gastro(UK).
Assistant Professor of Medicine and Gastroenterologist, Combined Military Hospital Kharian Cantt Pakistan.
Pak J Med Sci. 2016 Jul-Aug;32(4):896-89. doi: 10.12669/pjms.324.9645.
To compare the effectiveness of pain relief of Sucralfate and lidocain antacid 50:50 solution in post esophageal variceal band ligation pain.
All patients who had under gone Esophageal Variceal Band Ligation (EVBL) were included in the study. Patients un-willing to be included in the study or those who didn't have post EVBL pain were excluded. Patients with post EVBL pains were divided into two groups: one group was given sucralfate and other was given lidocaine: antacid 50:50 solution. Both were inquired about the duration of the pain relief after the medication. The results were analyzed on SPSS 23. Independent samples T-test was performed to find out whether the difference in duration of pain relief was significantly different in the two groups.
Out of 110 patients who have EVBL, 66(60.00%) had pain and 44(40.00%) were pain free. In the pain group 46 (69.7%) were given sucralfate and 20 (30.3%) were given lidocain: antacid 50:50 solution. Mean duration of pain relief in two groups was 2.78 (SD ± 2.096) and 2.5 days (SD ±. 0.76) respectively. Independent samples T-test results revealed that there was no statistically significant difference in the duration of pain relief between these two groups with p value 0.426.
Both Sucralfate and Lidocain: antacid 50:50 solutions are effective in relieving the post EVBL pain. However, no statistically significant difference in duration of pain relief was detected in separate groups of patients treated with either treatment.
比较硫糖铝与利多卡因抗酸剂1:1溶液缓解食管静脉曲张套扎术后疼痛的效果。
所有接受食管静脉曲张套扎术（EVBL）的患者均纳入本研究。不愿意纳入研究或无食管静脉曲张套扎术后疼痛的患者被排除。食管静脉曲张套扎术后疼痛的患者分为两组：一组给予硫糖铝，另一组给予利多卡因：抗酸剂1:1溶液。询问两组患者用药后疼痛缓解的持续时间。结果采用SPSS 23进行分析。进行独立样本t检验以确定两组疼痛缓解持续时间的差异是否具有统计学意义。
在110例接受食管静脉曲张套扎术的患者中，66例（60.00%）有疼痛，44例（40.00%）无疼痛。在疼痛组中，46例（69.7%）给予硫糖铝，20例（30.3%）给予利多卡因：抗酸剂1:1溶液。两组疼痛缓解的平均持续时间分别为2.78天（标准差±2.096）和2.5天（标准差±0.76）。独立样本t检验结果显示，两组疼痛缓解持续时间无统计学显著差异，p值为0.426。
硫糖铝和利多卡因：抗酸剂1:1溶液均能有效缓解食管静脉曲张套扎术后疼痛。然而，在接受这两种治疗的不同患者组中，未检测到疼痛缓解持续时间的统计学显著差异。
