Ernst E, Schenkel R, Weiland H, Matrai A, Heiss J
Department of Physical Medicine, MHH (Medical School), Hannover, FRG.
Burns. 1989 Aug;15(4):222-4. doi: 10.1016/0305-4179(89)90035-1.
Leucocyte aggregation describes one type of biophysical behaviour of white cells. To test whether this parameter is changed in burned patients, 15 burn victims were investigated immediately after admission into hospital. Cell counts and aggregation were measured and related to the prognosis of the injury. Compared with normal controls, burning injury is associated with higher white cell counts and enhanced leucocyte aggregation. Fatal injuries showed a (non-significant) tendency for higher aggregation values than survivors. There are significant positive correlations between white cell counts, maximal aggregation values and the burned body surface area. The results suggest that leucocyte aggregation is pathologically enhanced in response to burns. Possibly this alteration is of prognostic importance.
白细胞聚集描述了白细胞的一种生物物理行为。为了测试该参数在烧伤患者中是否发生变化,对15名烧伤患者入院后立即进行了调查。测量了细胞计数和聚集情况,并将其与损伤的预后相关联。与正常对照组相比,烧伤与更高的白细胞计数和增强的白细胞聚集有关。致命伤患者的聚集值有(无统计学意义的)高于幸存者的趋势。白细胞计数、最大聚集值与烧伤体表面积之间存在显著的正相关。结果表明,烧伤后白细胞聚集在病理上增强。这种改变可能具有预后意义。